Results 91 to 100 of about 2,267,096 (298)

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou   +16 more
wiley   +1 more source

Update on the Global Neurotrauma Outcomes Study Spine: An international, multi-centre, prospective cohort study on the injury profile, management and outcomes of traumatic spinal injury

open access: yesBrain and Spine, 2023
Saniya Mediratta   +13 more
doaj   +1 more source

Impact of bronchopulmonary dysplasia on brain and retina

open access: yesBiology Open, 2016
Many premature newborns develop bronchopulmonary dysplasia (BPD), a chronic lung disease resulting from prolonged mechanical ventilation and hyperoxia.
Annie Wing Hoi Poon   +7 more
doaj   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig   +9 more
wiley   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Prokineticin signaling in heart-brain developmental axis: Therapeutic options for heart and brain injuries

open access: yes, 2020
International audienceHeart and brain development occur simultaneously during the embryogenesis, and both organ development and injuries are interconnected.
Nebigil, Canan G   +2 more
core   +1 more source

Evaluation of cerebral concussion using the SCAT-5 tool: translation into Brazilian Portuguese and cultural adaptation [PDF]

open access: yesEinstein (São Paulo)
Objective: This study aimed to translate and culturally adapt the Sports Concussion Assessment Tool version 5 (SCAT-5) in Brazilian Portuguese for the follow-up of patients diagnosed with cerebral concussion. Methods: The components of the SCAT-5, which
Ana Camila de Castro Gandolfi   +4 more
doaj   +2 more sources

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird   +9 more
wiley   +1 more source

Investigating severe pediatric traumatic brain injury in South Africa : a demographic profile of admissions, brain oxygenation and neuropsychological outcomes and an attention-training intervention [PDF]

open access: yes, 2013
Includes bibliographical references.The aim of this dissertation was to investigate severe pediatric traumatic brain injury (pTBI) in South Africa. To that end, I conducted three studies, each examining a different aspect of severe pTBI. Study 1 presents
Schrieff, Leigh
core   +1 more source

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