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Traumatic brain injuries [PDF]

open access: yesNature Reviews Disease Primers, 2016
Traumatic brain injuries (TBIs) are clinically grouped by severity: mild, moderate and severe. Mild TBI (the least severe form) is synonymous with concussion and is typically caused by blunt non-penetrating head trauma. The trauma causes stretching and tearing of axons, which leads to diffuse axonal injury - the best-studied pathogenetic mechanism of ...
K. Blennow   +7 more
semanticscholar   +6 more sources

Activin A In Brain Injury

2007
Activin A is a growth factor composed of two betaA subunits belonging to the transforming growth factor beta (TGF-beta) superfamily of dimeric proteins. The biological activity of activin A is mediated by two different types of receptors, the type I (ARI and ARIB) and the type II receptors (ARII and ARIIB), and by two activin-binding proteins ...
Florio, Pasquale   +3 more
openaire   +4 more sources

Polyaminen and brain injury

Amino Acids, 1997
The cerebral ODC/polyamine system is disturbed by brain injury. The main modifications are important increases in ODC activity and putrescine concentration, with minor variations in spermidine and spermine concentrations. A great diversity of stimuli such as cerebral ischemia or overstimulation of the central nervous system by chemical or nonchemical ...
Vera, Núria de   +2 more
openaire   +3 more sources

Brain retraction injury

Voprosy neirokhirurgii imeni N.N. Burdenko, 2021
This review is devoted to various techniques for reduction of brain damage during retraction. Searching for reports was carried out in Russian and English languages using the PubMed database (n=721) without restrictions on language, date and study design according to the following keywords: «brain retraction injury», «spatula brain retractors ...
E.D. Grigorievskiy   +6 more
openaire   +2 more sources

Hypoglycemic brain injury

Seminars in Neonatology, 2001
Hypoglycemia frequently occurs in newborn infants who previously have suffered asphyxia, who are offspring of diabetic mothers, or who are low birthweight for gestational age (IUGR). Many infants who are hypoglycemic do not exhibit clinical manifestations, while others are symptomatic and at risk for the occurrence of permanent brain damage.
Robert C. Vannucci, Susan J. Vannucci
openaire   +3 more sources

A population-based study of seizures after traumatic brain injuries.

New England Journal of Medicine, 1998
BACKGROUND The risk of seizures is increased after traumatic brain injury, but the extent and duration of the increase in risk are unknown. The purpose of this study was to identify the characteristics of brain injuries that are associated with the ...
Ohn   +8 more
semanticscholar   +1 more source

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