Results 151 to 160 of about 3,236,915 (301)

Nationwide Survey of Association Between Fever and Epileptic Seizure in CDKL5 Deficiency Disorder Revealed Therapeutic Implications

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective CDKL5 deficiency disorder (CDD) is a rare, severe developmental and epileptic encephalopathy. There is a pressing need to develop effective and sustainable therapeutic strategies. We aimed to investigate the causal association between febrile episodes and epileptic seizures for therapeutic implications in CDD patients.
Siyi Wang, Jialin Du, Jinghui Liu, Dongmei Hu, Hongxin Wang, Xiaoxiao Man, Lehong Gao, Shimin Hu, Xianghong Meng, Hongyang Zhao, Minjing Hu, Yingxue Yang, Zhiqi Xiong, Liankun Ren   +13 more
wiley   +1 more source

Changes in Immune‐Inflammation Status and Prognosis in Pregnancy‐Related Cerebral Venous Thrombosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Distinguishing pathological changes from physiological adaptations in pregnancy‐related cerebral venous thrombosis (CVT) is clinically challenging. This study aimed to characterize coagulation, immune‐inflammation, and dehydration status in these patients and assess their prognostic value.
Xiaoming Zhang, Zilin Xu, Ran Duan, Chunxiao Lu, Da Zhou, Chen Zhou, Ran Meng, Xunming Ji   +7 more
wiley   +1 more source

Metabolic and Fluid Biomarkers Support Microglia Activation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis is an incurable neurodegenerative disease involving motor neuron degeneration and metabolic and immune dysfunction. We combined clinical data, cerebrospinal fluid biomarkers and fluorodeoxyglucose positron emission tomography with magnetic resonance imaging to investigate the role of reactive microglia in disease ...
Matteo Zanovello, Francesca Serani, Alen Bebeti, Federica Paredi, Giulia Quadrio, Andrea Fortuna, Giacomo Maria Minicuci, Elena Pegoraro, Annachiara Cagnin, Diego Cecchin, Gianni Sorarù   +10 more
wiley   +1 more source

Capillary stalling after traumatic brain injury: an emerging microcirculatory contributor to secondary brain injury. [PDF]

Front Neurol
Lei X, Yang Y, Yang X, Tao K.
europepmc   +1 more source

Alzheimer's Disease Biomarkers Measured by Capillary Blood Collection Versus Venous Plasma and Cerebrospinal Fluid

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Blood biomarkers are increasingly critical for non‐invasive Alzheimer's Disease (AD) diagnostics and research but typically require on‐site processing. Remote point‐of‐care collection methods could enhance biomarker testing in clinical and research settings.
Sara Ho, Ziling Shen, Alexandria Lewis, Megha Patel, Anny Zheng, Gianna Proscino, Thaovy Ho, Jiangxia Wang, Marilyn Albert, Abhay Moghekar   +9 more
wiley   +1 more source

Traumatic Brain Injury and the Road to Alzheimer's Disease. [PDF]

Biomedicines
Kaveh R, Kamari F, Høilund-Carlsen PF, Blaabjerg M, Christensen AA, Poulsen FR, Ghaedi S, Alavi A, Andalib S.   +8 more
europepmc   +1 more source

Updated Review of the Management of and Guidelines for Traumatic Brain Injury

Traumatic brain injury (TBI) remains a leading cause of mortality and disability globally, necessitating ongoing research into its pathophysiology and management. This review compiles current knowledge on TBI, focusing on its mechanisms, updated clinical
Aaron Rapp, Hassan Kobeissi, Daniel K. Fahim, Kobeissi, Hassan, Rapp, Aaron, Fahim, Daniel K   +5 more
core   +1 more source

Utility of the APE2 Score as a Diagnostic Tool for Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To retrospectively evaluate the diagnostic performance of the Antibody Prevalence in Epilepsy and Encephalopathy (APE2) score relative to clinician‐adjudicated autoimmune encephalitis (AE) and the Graus criteria in a tertiary neuroimmunology referral cohort, including antibody‐negative AE.
Bijoya Basu, Sophia F. Damman, Samhitha M. Rai, Hesham Abboud   +3 more
wiley   +1 more source

Carbon Nanotube–Based Strategies for Spinal Cord Injury: A PRISMA-Guided Systematic Review of Functionalization, Mechanisms, and Therapeutic Outcomes

Journal of Nanotechnology
Samine Mashayekhi, Bita Fazel, Sepideh Moradkhani, Masoud Vazirzadeh, Seyed Amir Hossein Javadi, Seyed Khalil Pestehei, Sadegh Bizhani Sharif, Sepideh Khodaparast, Alireza Karimi   +8 more
doaj   +1 more source

Modernizing Brain Injury Services in British Columbia: Developing Research Priorities for Children and Youth with Acquired Brain Injury. [PDF]

Healthcare (Basel)
Ramsay S, Harasym JA, MacRae W, Seidel D, Raamsdonk RV, Schmidt J, Cairncross M, Paneka W, Silverberg N, van Donkelaar P, Babul S, Price R, Hale O.   +12 more
europepmc   +1 more source