Results 181 to 190 of about 1,318,035 (358)

Promoting the process of determining brain death through standardized training

open access: yesFrontiers in Neurology
ObjectiveThis study aims to explore the training mode for brain death determination to ensure the quality of subsequent brain death determination.MethodsA four-skill and four-step (FFT) training model was adopted, which included a clinical neurological ...
Yingying Su   +17 more
doaj   +1 more source

Motor‐Free Soft Robots for Cancer Detection, Surgery, and In Situ Bioprinting

open access: yesAdvanced Healthcare Materials, EarlyView.
Novel motor‐free soft robots for cancer detection, surgery, and in situ bioprinting–are presented. This master‐slave system is constructed from soft fibrous syringe architectures, removing the need for electrical motors and complex control mechanisms, while reducing the physical tremors.
Chi Cong Nguyen   +17 more
wiley   +1 more source

Rod‐shaped Polymerized Salicylic Acid Particles Modulate Neutrophil Transendothelial Migration in Acute Inflammation

open access: yesAdvanced Healthcare Materials, EarlyView.
Rod‐shaped particles outperform spherical particles of the same volume in preventing neutrophil infiltration to inflamed areas, both in vitro and in vivo. This therapeutic effectiveness is attributed to better cell targeting and decreased cell motility, resulting from the geometry‐driven phagocytosis and inhibited actin polymerization.
M. Valentina Guevara   +7 more
wiley   +1 more source

A biomechanical study of neck strength and impact dynamics on head and neck injury parameters [PDF]

open access: yesarXiv
Traumatic brain injuries (TBI) are considered a silent epidemic. It affects many people, from automobiles to sports to service members. In this study, we employed a musculoskeletal head-neck model to understand the effect of impact locations, characteristics, and neck strength on head and neck injury severity. Three types of impact forces were studied:
arxiv  

Engineered Chitosan‐Derived Nanocarrier for Efficient siRNA Delivery to Peripheral and Central Neurons

open access: yesAdvanced Healthcare Materials, EarlyView.
This study introduces a novel chitosan‐based nanocarrier functionalized with a neurotropic protein for efficient siRNA delivery to neurons. The polyplexes demonstrate enhanced neuronal binding, retrograde transport, and PTEN silencing, promoting axonal outgrowth.
Ana P. Spencer   +10 more
wiley   +1 more source

β‐1,3 Glucan Microparticles & Nanoparticles: Fabrication Methods & Applications in Immunomodulation & Targeted Drug Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
Beta‐glucans have gained significant attention as an immunomodulatory biomaterial with cell‐targeting capabilities. This review comprehensively outlines the design and fabrication methods for producing beta‐glucan particles at both the micro and nanoscale and their applications in immune cell targeting, immunomodulation, and drug delivery ...
Nate Dowdall, Todd Hoare
wiley   +1 more source

Erratum to: A manual-based vocational rehabilitation program for patients with an acquired brain injury: study protocol of a pragmatic randomized controlled trial (RCT)

open access: yesTrials, 2017
Louise K. Hoeffding   +8 more
doaj   +1 more source

A Bio‐Inspired Perspective on Materials Sustainability

open access: yesAdvanced Materials, EarlyView.
This perspective discusses natural materials as inspiration for sustainable engineering designs and the processing of materials. First, circularity, longevity, parsimony, and activity are presented as essential material paradigms. The perspective then uses many examples of natural and technical materials to introduce principles such as oligo ...
Wolfgang Wagermaier   +2 more
wiley   +1 more source

Engineering CAR‐T Therapeutics for Enhanced Solid Tumor Targeting

open access: yesAdvanced Materials, EarlyView.
CART cell therapy has proven effective for blood cancers but struggles with solid tumors due to diverse antigens and complex environments. Recent efforts focus on improving CAR design and validation platforms. Advances in protein engineering, machine learning, and organoid systems aim to enhance CAR‐T therapy against solid tumors.
Danqing Zhu   +4 more
wiley   +1 more source

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