Results 251 to 260 of about 690,249 (294)

The Morphological, Behavioral, and Transcriptomic Life Cycle of Anthrobots

Advanced Science, EarlyView.
DNA is thought to determine shape, behavior, and lifespan, with developmental plasticity reserved for stem cells, embryos, and species like amphibia. How much morphogenetic plasticity do adult somatic human cells exhibit? Anthrobots are a self‐organizing, motile synthetic living construct made of genetically normal human epithelial cells.
Gizem Gumuskaya, Nikolai Davey, Pranjal Srivastava, Andrew Bender, Léo Pio‐Lopez, Douglas Hazel, Michael Levin   +6 more
wiley   +1 more source

From vulnerability to resilience: unraveling the role of oxidative stress in preterm brain injury. [PDF]

Ital J Pediatr
Jiang Q, Wen J, Ding Y, Cui H.
europepmc   +1 more source

EGR1 Promotes Craniofacial Bone Regeneration via Activation of ALPL⁺PDGFD⁺ Periosteal Stem Cells

Advanced Science, EarlyView.
ALPL+PDGFD+ (AP+) cells are distinct calvarial periosteal stem cells (PeSCs) with diminished postnatal activity. EGR1 drives PeSCs development via BMP signaling through its Znf2 domain and activates them via CTNNB1/WNT10B signaling through its Znf2/3 domains.
Yang Li, Dazhuang Lu, Fanqing Xu, Jun Yang, Dong Li, Chenlong Yang, Xin Chen, Xu Wang, Jia Qing, Hui Zhang, Yingfei Zhang, Fuchou Tang, Jie Qiao, Ophir D. Klein, Ping Zhang, Yongsheng Zhou   +15 more
wiley   +1 more source

Protective Effects of Deer Antler Peptides on D-Galactose-Induced Brain Injury. [PDF]

Nutrients
Chen S, Zong Y, Li J, He Z, Du R.
europepmc   +1 more source

Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy

Advanced Science, EarlyView.
In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao, Tian Shen, Shengda Cao, Ziyi Liu, Wendu Pang, Meixuan Li, Jingjing Liu, Wen Li, Yunhao Wu, Chengcheng Liu, Ming Xia, Xiaolong Fu, Cheng Cheng   +12 more
wiley   +1 more source

Nerve Growth Factor in Pediatric Brain Injury: From Bench to Bedside. [PDF]

Pharmaceuticals (Basel)
Di Sarno L, Ferretti S, Capossela L, Gatto A, Pansini V, Caroselli A, Manni L, Soligo M, Chiaretti A.   +8 more
europepmc   +1 more source

The Reconstruction of Peripheral Auditory Circuit: Recent Advances and Future Challenges

Advanced Science, EarlyView.
This paper summarizes the potential of biomaterials, stem cells, and gene editing technologies in the regeneration of inner ear hair cells, spiral ganglion neurons, and inner ear organoids. Challenges and potential developments are discussed and explored.
Zhe Li, Ying Zhang, Zhenyu Xiao, Jieyu Qi   +3 more
wiley   +1 more source

Pediatric traumatic brain injury and later psychotic syndromes in Finland. [PDF]

Eur J Pediatr
Laaksonen J, Ponkilainen V, Möttönen J, Mattila VM, Kuitunen I.   +4 more
europepmc   +1 more source

Rational Design of Inner Ear Drug Delivery Systems

Advanced Science, EarlyView.
Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu, Zhiyan Xuan, Haoyu Ren, Keng Chen, Hui Zhang, Huan Wang   +5 more
wiley   +1 more source

Immunosuppressive Formulations for Immunological Defense against Traumatic Brain Injury. [PDF]

Adv Healthc Mater
Lintecum K, Thumsi A, Dunn K, Druschel L, Chimene S, Prieto DF, Simmons A, Mantri S, Esrafili A, Swaminathan SJ, Trivedi M, Anandan S, Willingham C, Davila A, Inamdar S, Mangal JL, Suresh AP, Kasthuri NM, Jaggarapu MMCS, Appel N, Khodaei T, Ng ND, Sundem A, Pathak S, Bjorklund G, Newbern J, Capadona J, Stabenfeldt SE, Acharya AP.   +28 more
europepmc   +1 more source