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Traumatic brain injuries [PDF]
Nature Reviews Disease Primers, 2016 Traumatic brain injuries (TBIs) are clinically grouped by severity: mild, moderate and severe. Mild TBI (the least severe form) is synonymous with concussion and is typically caused by blunt non-penetrating head trauma. The trauma causes stretching and tearing of axons, which leads to diffuse axonal injury - the best-studied pathogenetic mechanism of ...
Jamie Toombs, Kaj Blennow
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International Anesthesiology Clinics, 2007
Traumatic brain injury (TBI) is a significant source of morbidity and mortality throughout the world. This article discusses the epidemiology, pathophysiology, and clinical presentations of minor, moderate, and severe TBI. Controversial topics, such as hypertonic saline for increased intracranial pressure, prehospital intubation of patients who have ...
Samir, Parikh +2 more
openaire +4 more sources
Traumatic brain injury (TBI) is a significant source of morbidity and mortality throughout the world. This article discusses the epidemiology, pathophysiology, and clinical presentations of minor, moderate, and severe TBI. Controversial topics, such as hypertonic saline for increased intracranial pressure, prehospital intubation of patients who have ...
Samir, Parikh +2 more
openaire +4 more sources
2007
Activin A is a growth factor composed of two betaA subunits belonging to the transforming growth factor beta (TGF-beta) superfamily of dimeric proteins. The biological activity of activin A is mediated by two different types of receptors, the type I (ARI and ARIB) and the type II receptors (ARII and ARIIB), and by two activin-binding proteins ...
Florio, Pasquale +3 more
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Activin A is a growth factor composed of two betaA subunits belonging to the transforming growth factor beta (TGF-beta) superfamily of dimeric proteins. The biological activity of activin A is mediated by two different types of receptors, the type I (ARI and ARIB) and the type II receptors (ARII and ARIIB), and by two activin-binding proteins ...
Florio, Pasquale +3 more
openaire +3 more sources
Overdose Risk and Brain Injury (Traumatic Brain Injury/Acquired Brain Injury), A Commentary
Substance Use & MisuseThis commentary seeks to evaluate existing knowledge about the relationship between brain injury (BI) and overdose (OD), to unify distant bodies of literature, and to enhance prevention and treatment for opioid OD among individuals with BI.There is a hidden epidemic of undiagnosed BI in the United States.
Samuel I. Martin +3 more
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Neurological Research, 2013
Traumatic brain injury (TBI) is one of the leading causes of death and disability world wide. In the United States alone, nearly 1·7 million individuals are treated in the hospital setting for TBI of all severities, which accounts for over US$48 billion of health care cost annually.
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Traumatic brain injury (TBI) is one of the leading causes of death and disability world wide. In the United States alone, nearly 1·7 million individuals are treated in the hospital setting for TBI of all severities, which accounts for over US$48 billion of health care cost annually.
openaire +2 more sources
Voprosy neirokhirurgii imeni N.N. Burdenko, 2021
This review is devoted to various techniques for reduction of brain damage during retraction. Searching for reports was carried out in Russian and English languages using the PubMed database (n=721) without restrictions on language, date and study design according to the following keywords: «brain retraction injury», «spatula brain retractors ...
N A, Polunina +6 more
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This review is devoted to various techniques for reduction of brain damage during retraction. Searching for reports was carried out in Russian and English languages using the PubMed database (n=721) without restrictions on language, date and study design according to the following keywords: «brain retraction injury», «spatula brain retractors ...
N A, Polunina +6 more
openaire +2 more sources
The neurophysiology of brain injury
Clinical Neurophysiology, 2004This article reviews the mechanisms and pathophysiology of traumatic brain injury (TBI).Research on the pathophysiology of diffuse and focal TBI is reviewed with an emphasis on damage that occurs at the cellular level. The mechanisms of injury are discussed in detail including the factors and time course associated with mild to severe diffuse injury as
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2008
Despite prevention efforts, pediatric head trauma remains the most common cause of serious injury and death in children. Seventy-five percent of children who are hospitalized secondary to trauma, sustain head trauma. Most pediatric head trauma is mild in severity, although central nervous system (CNS) injury is the most common cause of pediatric ...
S Scott, Lollis +2 more
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Despite prevention efforts, pediatric head trauma remains the most common cause of serious injury and death in children. Seventy-five percent of children who are hospitalized secondary to trauma, sustain head trauma. Most pediatric head trauma is mild in severity, although central nervous system (CNS) injury is the most common cause of pediatric ...
S Scott, Lollis +2 more
openaire +2 more sources
New England Journal of Medicine, 2004
More than 95 percent of infants who have neonatal stroke survive to adulthood, and many have residual motor or cognitive disabilities. This article makes the point that recognition of at-risk newborns by means of advanced methods of neuroimaging, combined with a plan for rational intervention, may result in the prevention or the reduction in the ...
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More than 95 percent of infants who have neonatal stroke survive to adulthood, and many have residual motor or cognitive disabilities. This article makes the point that recognition of at-risk newborns by means of advanced methods of neuroimaging, combined with a plan for rational intervention, may result in the prevention or the reduction in the ...
openaire +2 more sources
Seminars in Neurology, 2015
Traumatic brain injury (TBI) is a major cause of traumatic death and disability In the US, a brain injury occurs every 7 s and results in death every 5 min ∼52,000 patients die from TBI each year TBI accounts for nearly one-third of all trauma-related deaths Common mechanisms include falls, motor vehicle accidents, and assaults In the US, most TBIs are
openaire +2 more sources
Traumatic brain injury (TBI) is a major cause of traumatic death and disability In the US, a brain injury occurs every 7 s and results in death every 5 min ∼52,000 patients die from TBI each year TBI accounts for nearly one-third of all trauma-related deaths Common mechanisms include falls, motor vehicle accidents, and assaults In the US, most TBIs are
openaire +2 more sources