Results 151 to 160 of about 2,529,991 (308)
Advanced Science, EarlyView.Omicsformer, a deep learning model, integrates multi‐omics and routine blood data to accurately predict risks for nine chronic diseases, including cancer and cardiovascular conditions. Validated using large scale clinical data, it reveals early risk trajectories, advancing personalized medicine and offering a cost‐effective, community‐based solution ...
Zhibin Dong +20 more
wiley +1 more source
Experimental focal ischemia in cats: changes in multimodality evoked potentials as related to local cerebral blood flow and ischemic brain edema. [PDF]
, 1987 Keisuke Kataoka +3 more
openalex +1 more source
A Program for Solving the Brain Ischemia Problem
Brain Sciences, 2013 Our recently described nonlinear dynamical model of cell injury is here applied to the problems of brain ischemia and neuroprotection. We discuss measurement of global brain ischemia injury dynamics by time course analysis.
Donald J. DeGracia
doaj +1 more source
Advanced Science, EarlyView.Utilizing a stereotaxic injection mouse model and a novel mathematical approach, this study uncovers key subnetworks that drive pathological α‐synuclein (α‐Syn) progression in Parkinson's disease (PD). Remarkably, just 2% of the strongest connections in the connectome are sufficient to predict its spread.
Yuanxi Li +16 more
wiley +1 more source
Inhibition of central angiotensin-converting enzyme with enalapril protects the brain from ischemia/reperfusion injury in normotensive rat [PDF]
Background and the Purpose of the study: Central Angiotensin Converting Enzyme (ACE) has an important role on cerebral microcirculation and metabolism.
دهقان, غلامعباس +1 more
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Cerebral Ischemia and Reperfusion: Prevention of Brain Mitochondrial Injury by Lidoflazine [PDF]
, 1987 Robert E. Rosenthal +4 more
openalex +1 more source
2-vessel occlusion/hypotension: a rat model of global brain ischemia.
Journal of Visualized Experiments, 2013 Cardiac arrest followed by resuscitation often results in dramatic brain damage caused by ischemia and subsequent reperfusion of the brain. Global brain ischemia produces damage to specific brain regions shown to be highly sensitive to ischemia (1 ...
Thomas H. Sanderson, Joseph M. Wider
semanticscholar +1 more source
Genetics‐Based Targeting Strategies for Precise Neuromodulation
Advanced Science, EarlyView.In this Review, the fundamental principles and implementation protocols of genetics‐based precision neuromodulation are first introduced. Then, wireless and low‐invasive strategies based on nano‐transducing materials are highlighted, along with a dissection and analysis of the strengths and weaknesses of representative studies.
Yuyuan He +11 more
wiley +1 more source
Advanced Science, EarlyView.In multiple sclerosis, the disruption of the blood‐spinal cord barrier (BSCB) induced by CXCL13 facilitates the infiltration of inflammatory cells into the central nervous system, resulting in demyelination and neuronal injury. Mechanistically, the deleterious impact of CXCL13 on the BSCB is associated with a reduction in tight junction protein ...
Jingjing Han +10 more
wiley +1 more source
Hypoxia-inducible factor: role in cell survival in superoxide dismutase overexpressing mice after neonatal hypoxia-ischemia. [PDF]
, 2019 BackgroundSixty percent of infants with severe neonatal hypoxic-ischemic encephalopathy die, while most survivors have permanent disabilities. Treatment for neonatal hypoxic-ischemic encephalopathy is limited to therapeutic hypothermia, but it does not ...
Ferriero, Donna M +2 more
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