Results 161 to 170 of about 358,469 (348)
Nanocatalytic Neuroprotection and Neurological Recovery Post‐Traumatic Brain Injury
Advanced Science, EarlyView.This study demonstrates that combining Ce0.7Zr0.3O2 nanozymes with nimodipine enhances neuroprotection after traumatic brain injury. The therapy reduces oxidative stress, neuronal apoptosis, and improves blood–brain barrier integrity, with nanozymes effective at low doses.
Xinjie Hong +10 more
wiley +1 more source
Astrocytic TRPV4 Channels and Their Role in Brain Ischemia. [PDF]
Int J Mol Sci, 2023 Tureckova J +3 more
europepmc +1 more source
The Significance of Brain Temperature in Focal Cerebral Ischemia: Histopathological Consequences of Middle Cerebral Artery Occlusion in the Rat [PDF]
, 1992 Eiharu Morikawa +6 more
openalex +1 more source
Human Brain Cell‐Type‐Specific Aging Clocks Based on Single‐Nuclei Transcriptomics
Advanced Science, EarlyView.Muralidharan and colleagues develop cell‐type‐specific transcriptomic aging clocks using single‐nucleus RNA sequencing of human post mortem prefrontal cortex samples. These clocks accurately predict age and identify distinct aging trajectories in specific brain cell types.
Chandramouli Muralidharan +12 more
wiley +1 more source
Autoregulation of Cerebral Blood Flow in Experimental Focal Brain Ischemia [PDF]
, 1990 Ulrich Dirnagl, William A. Pulsinelli
openalex +1 more source
Advanced Science, EarlyView.Shear‐activated nanoparticles carrying nitroglycerin selectively target high‐shear stress collateral vessels during ischaemic stroke, enhancing blood flow to at‐risk brain without systemic side effects. This novel approach significantly improves outcomes in animal models, outperforming conventional nitroglycerin delivery.
Magdalena Litman +21 more
wiley +1 more source
MiR-126 and miR-146a as Melatonin-Responsive Biomarkers for Neonatal Brain Ischemia. [PDF]
J Mol Neurosci, 2023 Albertini MC +7 more
europepmc +1 more source
Macrophage Zc3h12c Limits Tissue Inflammation and Injury via Alternative Splicing of Pre‐mRNA
Advanced Science, EarlyView.This work defines the context‐dependent function of Zc3h12c in macrophages using the Tnfrsf11a‐Cre system. It reveals Zc3h12c's dual mechanism—regulating RNA degradation and alternative splicing—with STAT1 as a key target. The findings elucidate a novel post‐transcriptional pathway and identify STAT1 isoforms as potential therapeutic targets for kidney
Chenyu Li +14 more
wiley +1 more source