Results 161 to 170 of about 2,811,049 (348)

THE mRNA EXPRESSION CHARACTER OF HIF-1?AND HIF-3?, NITROTYROSINE, �GMP AND INTERLEUKINS IN THE MONGOLIAN GERBILS BRAIN WITH ACUTE ISCHEMIA DURING THE GLUTATHIONE SYSTEM MODULATORS THERAPY

, 2018
И. Ф. Беленичев, Olena Semenivna Lytvynenko, Oleksandr Kamyshnyi   +2 more
openalex   +1 more source

Novel Docosanoids Inhibit Brain Ischemia-Reperfusion-mediated Leukocyte Infiltration and Pro-inflammatory Gene Expression [PDF]

, 2003
Victor L. Marcheselli, Song Hong, Walter J. Lukiw, Xiao Hua Tian, Karsten Gronert, Alberto E. Musto, Mattie Hardy, Juan Gimenez, Nan Chiang, Charles N. Serhan, Nicolás G. Bazán   +10 more
openalex   +1 more source

Platelet Rubicon Bidirectional Regulation of GPVI and Integrin αIIbβ3 Signaling Mitigates Stroke Infarction Without Compromising Hemostasis

Advanced Science, EarlyView.
This study identifies Rubicon as a key platelet protein that bidirectionally regulates GPVI and integrin αIIbβ3 signaling. Platelet Rubicon protects against cerebral ischemia‐reperfusion injury by limiting infarction without increasing hemorrhage.
Xiaoyan Chen, Jingke Li, Yangyang Liu, Li Li, Xin Deng, Yilin Sheng, Xianyu Zhu, Xiao Jiang, Wei Li, Xueli Cai, Qiming Sun, Hu Hu   +11 more
wiley   +1 more source

Rapamycin prevents cerebral stroke by modulating apoptosis and autophagy in penumbra in rats [PDF]

, 2018
Bové, Calastretti, Carloni, Castedo, Castedo, Chauhan, Chen, Chong, Chong, Donnan, Ferri, Flynn, Fu, Genova, Harada, Hwang, Hwang, Jiang, Kofman, Koh, Li, Li, Lu, Lu, Maiese, Rieker, Sanghera, Santini, Schmued, Shahjouei, Siddiqui, Thyrell, Urbanek, Wang, Wang, Wechsler, Wong, Xie, Xie, Yang, Yin, Zare, Zeng   +42 more
core   +2 more sources

Efficacy of inhaled HYdrogen on neurological outcome following BRain Ischemia During post-cardiac arrest care (HYBRID II trial): study protocol for a randomized controlled trial [PDF]

, 2017
Tomoyoshi Tamura, Kei Hayashida, Motoaki Sano, Shuko Onuki, Masaru Suzuki   +4 more
openalex   +1 more source

Dysfunctional TRIM31 of POMC Neurons Provokes Hypothalamic Injury and Peripheral Metabolic Disorder under Long‐Term Fine Particulate Matter Exposure

Advanced Science, EarlyView.
Particulate matter ≤2.5 µm (PM2.5) elevates risks of neurological and chronic metabolic diseases, but the underlying mechanisms linking PM2.5‐induced central nervous system (CNS) injury to metabolic dysfunction remain unclear. Hypothalamic pro‐opiomelanocortin‐expressing (POMC+) neurons regulate systemic metabolic homeostasis, and tripartite motif ...
Chenxu Ge, Jiamao Lin, Changsheng Yang, Chuanwang Miao, Fengxiang Li, Shuqiang Zhao, Lei Zou, Xuedong Teng, Lina Liu, Tingguang Li, Yan Sun, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Minxuan Xu, Minghui Chang, Jun Tan, Yanrong Ren, Bochu Wang   +21 more
wiley   +1 more source

Haploinsufficiency in the mitochondrial protein CHCHD4 reduces brain injury in a mouse model of neonatal hypoxia-ischemia [PDF]

, 2017
Yanyan Sun, Tao Li, Cuicui Xie, Yiran Xu, Kai Zhou, Juan Rodríguez, Wei Han, Xiaoyang Wang, Guido Kroemer, Nazanine Modjtahedi, Klas Blomgren, Changlian Zhu   +11 more
openalex   +1 more source

NLRP3 inflammasome activation increases brain oxidative stress after transient global cerebral ischemia in rats

, 2021
Larissa Joaquim, Lucinéia Gainski Danielski, Sandra Bonfante, Erica Biehl, Khiany Mathias, Taís Luise Denicol, Érick Bagio, Everton Lanzzarin, Richard Simon Machado, Gabriela Bernades, Jaqueline S. Generoso, Amanda Della Giustina, Tatiana Barichello, Fabrícia Petronilho   +13 more
openalex   +2 more sources

TRIM56 Aggravates Cerebral Ischemia‐Reperfusion Injury via Inhibiting KLF4‐Activated Ferroptosis Signaling

Advanced Science, EarlyView.
This study reveals that the E3 ubiquitin ligase TRIM56 exacerbates neuronal ferroptosis and brain damage by mediating K48‐linked ubiquitination and degradation of KLF4, leading to suppression of the xCT/GSH/GPX4 axis. Targeting TRIM56 alleviates cerebral ischemia‐reperfusion injury in vivo and in vitro, highlighting its therapeutic potential.
Qiangping Wang, Shuang Li, Man Li, Wenke Zhou, Jianqing Zhang, Zhenfu Wu, Zhaoqi Mao, Juan Wan, Xinhao Tang, Baoping Zheng, Qiang Liu, Zhendong Li, Xiaobing Jiang, Qingping Wu, Youfan Ye, Haijun Wang   +15 more
wiley   +1 more source

Role of Mitochondrial Permeability Transition in the Immature Brain Following Intrauterine Ischemia

, 2007
Akihito Nakai
openalex   +2 more sources