Results 171 to 180 of about 329,254 (353)

TGIF1 overexpression promotes glioma progression and worsens patient prognosis

Cancer Medicine, Volume 11, Issue 24, Page 5113-5128, December 2022., 2022
This study is the first to comprehensively analyze and reveal TGIF1, as a new oncogene, is closely related to the malignancy‐related phenotype of glioma, and that TGIF1 could be an independent risk factor for poor prognosis of glioma, which is expected to become a new target for individualized treatment of glioma patients.
Baoya Wang, Qiong Ma, Xuelin Wang, Kunshan Guo, Zhendong Liu, Gang Li   +5 more
wiley   +1 more source

Effect of Exercise Preconditioning on Memory Deficits and Neuronal Cell Death in the CA3 Pyramidal Cells of the Rat Hippocampus Following Transient Global Cerebral Ischemia

Journal of Ardabil University of Medical Sciences, 2015
Background & objectives: Brain ischemia leads to irreversible functional and structural damage in various regions of the brain, especially in the hippocampus.
N Shamsaei, N Aboutaleb, S Erfani, M Khaksari   +3 more
doaj  

Potassium channel activators protect the N-methyl-D-aspartate-induced cerebral vascular dilation after combined hypoxia and ischemia in piglets [PDF]

, 1998
Background and Purpose-Cerebral arteriolar dilation to N-methyl-D-aspartate (NMDA) is a neuronally mediated multistep process that is sensitive to cerebral hypoxia and ischemia (H/I).
Bari, Ferenc, Domoki, Ferenc, Veltkamp, R.   +2 more
core  

Effect of nimodipine on cerebral functional and metabolic recovery following ischemia in the rat brain. [PDF]

, 1986
Hideo Mabe, Hiroyuki Nagai, Tsutomu Takagi, S Umemura, Masuo Ohno   +4 more
openalex   +1 more source

Microenvironmental Modulation for Therapeutic Efficacy of Extracellular Vesicles

Advanced Science, EarlyView.
Recent studies highlighted the heterogeneity of EVs and the influence of microenvironmental signals on their therapeutic efficacy. This review offers a comprehensive overview of strategies and mechanisms to optimize the therapeutic efficacy of EVs through physical, biochemical, and mechanical modulation.
Bilu Xiang, Shiying Zhang, Irene Shuping Zhao, Xueqi Gan, Yang Zhang   +4 more
wiley   +1 more source

Exosomes and their roles in the chemoresistance of pancreatic cancer

Cancer Medicine, Volume 11, Issue 24, Page 4979-4988, December 2022., 2022
Despite the development of multiple promising chemotherapeutic agents as recommended first‐line treatment for PC, the therapeutic efficacy is largely limited by unwanted drug resistance.Exploring the relation between exosomes and chemoresistance may be conducive to understanding molecular mechanisms and taking effective measures to reduce the ...
Yubin Pan, Honglin Tang, Qijun Li, Guangpeng Chen, Da Li   +4 more
wiley   +1 more source

Opioid peptide levels in gerbil brain after transient ischemia: lasting depletion of hippocampal dynorphin. [PDF]

, 1987
Richard L. Fried, T Nowak
openalex   +1 more source

Hypoxia-inducible factor: role in cell survival in superoxide dismutase overexpressing mice after neonatal hypoxia-ischemia. [PDF]

, 2019
BackgroundSixty percent of infants with severe neonatal hypoxic-ischemic encephalopathy die, while most survivors have permanent disabilities. Treatment for neonatal hypoxic-ischemic encephalopathy is limited to therapeutic hypothermia, but it does not ...
Ferriero, Donna M, Jeon, Ga Won, Sheldon, R Ann   +2 more
core  

Time course of early brain edema following reversible forebrain ischemia in rats. [PDF]

, 1989
Pekka Mellergård, F. Bengtsson, Maj‐Lis Smith, Vendela Riesenfeld, Bo K. Siesjö   +4 more
openalex   +1 more source

Astrocytic TRPV4 Channels and Their Role in Brain Ischemia. [PDF]

Int J Mol Sci, 2023
Tureckova J, Hermanova Z, Marchetti V, Anderova M.   +3 more
europepmc   +1 more source