METABOLIC AND BEHAVIORAL EFFECTS OF KETOGENIC AND NON-KETOGENIC LOW-CARBOHYDRATE DIETS
Ilya Smolensky+4 more
doaj
The FGF13 level is significantly downregulated in premature aging murine hearts subject to D‐galactose and Doxorubicin. FGF13 overexpression and deficiency exacerbated and alleviated Doxorubicin/D‐galactose‐induced myocardial aging characteristics and functional impairment, respectively.
Enzhao Shen+15 more
wiley +1 more source
Effect of Ischemia on Known Substrates and Cofactors of the Glycolytic Pathway in Brain
Oliver H. Lowry+3 more
openalex +1 more source
Incomplete transient ischemia: a non-destructive evaluation of in vivo cerebral metabolism and hemodynamics in rat brain. [PDF]
N. Wiernsperger+2 more
openalex +1 more source
Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang+4 more
wiley +1 more source
Pial Arterial Responses in the Cat Brain Following Prolonged Ischemia
S. Takagi+3 more
openalex +2 more sources
Radiation Exposure Induced Blood–Brain Barrier Injury via Mitochondria‐Mediated Sterile Inflammation
This work describes a blood–brain barrier (BBB) microphysiological system (MPS) to explore the responses of BBB to radiation exposure. Following radiation exposure, obvious BBB comprise and brain endothelial injuries are detected. Mechanism study shows radiation induced significant sterile inflammation via mitochondrial dysfunction and cGAS‐STING ...
Peng Wang+6 more
wiley +1 more source
Delayed Transplantation of Neural Stem Cells Improves Initial Graft Survival after Stroke
Delayed transplantation of human iPSC‐derived neural progenitor cells (NPCs) enhances graft survival, proliferation, and axonal sprouting after stroke. Using bioluminescence imaging and histology in a mouse model of stroke, it is shown that NPC delivery at 7 days post‐stroke is more effective than acute transplantation, highlighting the importance of ...
Rebecca Z Weber+6 more
wiley +1 more source
Prolonged ischemia differently affects phospholipase C acting against phosphatidylinositol and phosphatidylinositol 4,5‐bisphosphate in brain subsynaptosomal fraction [PDF]
Joanna B. Strosznajder
openalex +1 more source
Multiscale Organization of Neural Networks in a 3D Bioprinted Matrix
A 3D bioprint model of primary neurons has been engineered with a millimeter‐scale functional neural network, and it recapitulates in vivo transcriptomic features under both normal and disease conditions to the greatest extent. The successful integration of mature neurons and 3D bioprinting signifies a major advance in neuroscience modeling ...
Huiyu Yang+16 more
wiley +1 more source