Results 181 to 190 of about 358,469 (348)

Therapeutic Potential of Natural Compounds for Brain Ischemia-Reperfusion Injury. [PDF]

Biology (Basel)
Yoo KY, Won MH, Ahn JH, Park JH.
europepmc   +1 more source

Exogenous oxygen is required for prostanoid induction under brain ischemia as evidence for a novel regulatory mechanism. [PDF]

J Lipid Res, 2023
Seeger DR, Schofield B, Besch D, Golovko SA, Kotha P, Parmer M, Solaymani-Mohammadi S, Golovko MY.   +7 more
europepmc   +1 more source

Evidence of Nuclear DNA Fragmentation Following Hypoxia‐Ischemia in the Infant Rat Brain, and Transient Forebrain Ischemia in the Adult Gerbil [PDF]

, 1994
Isidró Ferrer, Avelina Tortosa, Alfons Macaya, Àngels Sierra, Dolores Moreno, Francina Munell, Rosa Blanco, Waney Squier   +7 more
openalex   +1 more source

Microglia Drive Peripapillary Vascular Density Reduction in Normal Tension Glaucoma by Regulating the Rpl17/Stat5b/Apoa1 Axis

Advanced Science, EarlyView.
This study revealed that E50K mutant microglia drive retinal peripapillary vascular density reduction in NTG via the Rpl17/Stat5b/Apoa1 axis and identified Apoa1 as a novel suppressor of retinal vascular endothelial cells. These findings identify a potential therapeutic target for glaucoma and support the clinical potential of EA for protecting RGCs ...
Di Zhang, Sisi Chen, Yanfeng Zhang, Leyi Qiu, Mengxian Du, Wulian Song, Fengyi Guo, Jingyang Zhang, Xinna Liu, Huiping Yuan   +9 more
wiley   +1 more source

T817MA protects against inflammation and pyroptosis in response to brain ischemia via activating Sirt1 signaling. [PDF]

Sci Rep
Wang T, Pan YJ, Zhang MM, Wang X, Li W, Lv JM.   +5 more
europepmc   +1 more source

Sexual Dimorphism in Neurodegenerative Diseases and in Brain Ischemia. [PDF]

Biomolecules, 2022
Zalewska T, Pawelec P, Ziabska K, Ziemka-Nalecz M.   +3 more
europepmc   +1 more source

Protein kinase C alterations in the fetal rat brain after global ischemia.

, 1988
J.C. Louis, Ella Magal, Ephraïm Yavin
openalex   +1 more source

Targeting ROCK2 to Restore Epileptic Synaptic Networks via Mitophagy Activation: Insights from Translational Imaging of SV2A In Vivo

Advanced Science, EarlyView.
By integrating synaptic vesicle glycoprotein 2A PET imaging and transcriptomics, this study identifies Rho‐associated protein kinase 2 (ROCK2) as a critical regulator of synaptic network dysfunction in temporal lobe epilepsy. Pharmacological ROCK2 inhibition restores synaptic density and enhances mitophagy, thereby reducing seizures and neuronal damage.
Ling Xiao, Jing Wang, Bei Chen, Jinhui Yang, Fangyu Wu, Chunyao Zhou, Yifei Zhang, Zhiquan Yang, Dingyang Liu, Lei Tian, Jianhua Yu, Fei Han, Yongxiang Tang, Li Feng, Shuo Hu   +14 more
wiley   +1 more source

Exploring the protective effects of ischelium on rat brain ischemia-reperfusion injury. [PDF]

Sci Prog
Chen Y, Cheng W, Xiao B, Tang J, Kuang M, Xu L, Xu X, Liu H.   +7 more
europepmc   +1 more source

Clinically Inspired Multimodal Treatment Using Induced Neural Stem Cells‐Derived Exosomes Promotes Recovery of Traumatic Brain Injury through Microglial Modulation

Advanced Science, EarlyView.
This study explores the therapeutic potential of iNSC‐Exo via local and systemic delivery in TBI mice. It is found that iNSC‐Exo enhances NRXN signaling through Microglia_Nrg3 and Microglia_Rarb, effectively promoting functional and neurological recovery, suggesting a new therapeutic strategy for TBI. Abstract Traumatic brain injury (TBI) poses serious
Jiaojiao Li, Maoxiang Xu, Boyu Cai, Xiangyu Li, Zhanping Liang, Xiaohuan Xia, Haitao Zhang, Zhiwen Zhang, Fei Tan, Jialin Charlie Zheng   +9 more
wiley   +1 more source