Results 261 to 270 of about 2,811,049 (348)

Therapeutic Effects of Intranasal Administration of Resveratrol on the Rat Model of Brain Ischemia. [PDF]

Heliyon
Owjfard M, Rahimian Z, Ghaderpanah R, Rafiei E, Sadrian S, Sabaghan M, Karimi F.   +6 more
europepmc   +1 more source

Endothelial Cell‐Based Vascular Bandages for Blood–Brain Barrier Repair and Targeted siRNA Delivery

Advanced Science, EarlyView.
mECs restore blood–brain barrier function after cerebral ischemia–reperfusion by simultaneously targeting, supporting, and regulating the damaged vasculature. mECs home to injured cerebral vessels through interactions with highly expressed VLA‐4, reinforce endothelial integrity by forming new junctions, and, upon OGD‐SN treatment, acquire enhanced ...
Yaosheng Li, Yunfei Dong, Yaode He, Juanjuan Zheng, Hui Liu, Lu Li, Xiaoxu Hao, Yanli Zhao, Zefeng Yang, Yuankai Sun, Zhiwei Du, Bo Zhao, Weihang Zhou, Honghui Wu, Tianyuan Zhang, Jiahe Wu, Xiangrui Liu, Xianzhen Yin, Zhicai Chen, Rui Xue, Min Lou, Zhen Gu, Xinchi Jiang, Jianqing Gao   +23 more
wiley   +1 more source

In vivo mapping of cellular resolution neuropathology in brain ischemia with diffusion MRI. [PDF]

Sci Adv
Wu D, Lee HH, Ba R, Turnbill V, Wang X, Luo Y, Walczak P, Fieremans E, Novikov DS, Martin LJ, Northington FJ, Zhang J.   +11 more
europepmc   +1 more source

Expression of neuropeptide Y in rat brain ischemia

, 2013
Siniša Babović, Biljana Srdić, Branislava Soldatović-Stajić, Mina Cvjetković-Bošnjak, Bojana Krstonošić, Djendji Siladji-Mladenovic   +5 more
openalex   +2 more sources

AXL Promotes Ischemic Myelin Repair Through Alleviating Myelin Debris Deposition and Lipid Droplets Accumulation

Advanced Science, EarlyView.
Microglial AXL drives white matter repair after stroke by orchestrating the cleanup of myelin debris. Mechanistically, AXL signals through EGR1 to boost Smpd1 transcription, regulating sphingolipid metabolism and preventing lipid droplet toxicity. Restoring the pathway with ASM therapy mitigates damage, positioning AXL as a key node for therapeutic ...
Junqiu Jia, Yonghui Gan, Jia Li, Lilin Li, Hailan Meng, Min Sun, Lei Ye, Rui Mao, Xiang Cao, Shengnan Xia, Xinyu Bao, Renyuan Liu, Meijuan Zhang, Yun Xu   +13 more
wiley   +1 more source

Oxidative Metabolism in Brain Ischemia and Preconditioning: Two Sides of the Same Coin. [PDF]

Antioxidants (Basel)
D'Apolito E, Sisalli MJ, Tufano M, Annunziato L, Scorziello A.   +4 more
europepmc   +1 more source

Iron Oxide Nanozyme as Reactive Oxygen and Nitrogen Species Scavenger to Regulate Microglial Homeostasis in Stroke

Advanced Science, EarlyView.
6 nm iron oxide nanoparticles (IONP6) exhibit enzyme‐like activities that scavenge reactive oxygen and nitrogen species (RONS), including nitric oxide (NO). In stroke models, IONP6 promotes microglial polarization toward the M2 phenotype, reduces neuroinflammation, and improves neurological outcomes, offering a promising drug‐free approach to mitigate ...
Yilin Qi, Chunxiao Wang, Yuqing Miao, Jiamin Li, Zengyu Xun, Di Sun, Fei Xu, Minrui Liu, Heping Wang, Galong Li, Xuyi Chen, Haiming Fan, Xue Xue   +12 more
wiley   +1 more source

A neural cell automated analysis system based on pathological specimens in a gerbil brain ischemia model. [PDF]

Acta Cir Bras
Katsumata E, Ranjan AK, Tashima Y, Takahata T, Sato T, Kobayashi M, Ishii M, Takahashi T, Oda A, Hirano M, Hakamata Y, Sugai K, Kobayashi E.   +12 more
europepmc   +1 more source

Effectiveness of Pre‐Transplant Dual GLP‐1 Receptor Agonist and SGLT2 Inhibitor Therapy on All‐Cause Mortality in Organ Transplantation Candidates with Obesity and Type 2 Diabetes: a Target‐Trial Emulation

Advanced Science, EarlyView.
This target trial emulation in solid organ transplant candidates with obesity and type 2 diabetes evaluates whether pre‐transplant dual therapy with GLP‐1 receptor agonists plus SGLT2 inhibitors is associated with post‐transplant mortality and kidney graft outcomes compared with monotherapy or usual care, using multinational electronic health records ...
Yu‐Nan Huang, Min‐Yu Tsou, Pin‐Hung Li, Jo‐Ching Chen, Yen‐Liang Liu, Gideon Meyerowitz‐Katz, Tsung‐Hsun Tsai, Pen‐Hua Su   +7 more
wiley   +1 more source

Temporal expression profiles of microRNAs associated with acute phase of brain ischemia in gerbil hippocampus. [PDF]

Heliyon
Hamada Y, Takata T, Iwama H, Kawakita R, Nonaka W, Deguchi K, Kobara H, Morishita A, Miyamoto O, Nakamura T, Itano T, Masaki T.   +11 more
europepmc   +1 more source