Results 291 to 300 of about 358,469 (348)
Cytokine pathways driving diverse tissue pathologies in rheumatoid arthritis
Arthritis &Rheumatology, Accepted Article.Rheumatoid arthritis is a complex systemic disorder characterised primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease e.g. of the lung with potentially devastating clinical consequences.
Aurelie Najm +2 more
wiley +1 more source
Understanding aging effects on brain ischemia
Neurobiology of Disease, 2019 openaire +3 more sources
Biotechnology and Applied Biochemistry, EarlyView.ABSTRACT Senkyunolide I (Sen I) has a protective effect on the blood–brain barrier (BBB) in rats with sepsis‐associated encephalopathy (SAE). This study investigated whether Sen I regulates Nrf2 to ameliorate sepsis‐induced brain dysfunction (SIBD). Sixty rats were randomly assigned into Sham group, SAE group (Model group), SAE + Sen I group (72 mg/kg,
Haohao Cao, Tao Liu, Meixia Xu
wiley +1 more source
Cost–benefit analysis of screening programme for diabetic retinopathy in Bulgaria
British Journal of Clinical Pharmacology, EarlyView.Aims Late‐diagnosed diabetic retinopathy (DR) is difficult and expensive to treat. Screening programmes can identify the disease early and reduce the costs of its future treatment. This study aims to analyse the cost–benefit of screening programmes for DR.
Iva Nenkova +5 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Introduction Bevacizumab, a vascular endothelial growth factor inhibitor, is used off‐label for treatment of severe anaemia related to epistaxis, gastrointestinal bleeding and/or severe hepatic arteriovenous malformations (HAVM) and right‐sided cardiac failure in patients with hereditary haemorrhagic telangiectasia (HHT).
Pernille D. Haahr +18 more
wiley +1 more source
Combination of Hydrogen Inhalation and Hypothermic Temperature Control After Out-of-Hospital Cardiac Arrest: A Post hoc Analysis of the Efficacy of Inhaled Hydrogen on Neurologic Outcome Following Brain Ischemia During PostCardiac Arrest Care II Trial. [PDF]
Crit Care MedTamura T +4 more
europepmc +1 more source
Corrections to "Bone marrow mesenchymal stem cells in brain ischemia enhaces axonal regeneration associated with IGF-1". [PDF]
Ibraineuropepmc +1 more source
Gerontology, 1987 A 15-min complete cerebral ischemia, and repetitive ischemic insults of 15-min duration each cause changes in brain cortical glucose and energy metabolism which are similar in quality but different in quantity. Abnormalities in glycolytic flux, lactate production, cessation of oxidation and energy production were found to be more pronounced with ...
openaire +2 more sources
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Experientia, 1980
Hypertension was produced in anesthetized and conscious dogs when cerebral perfusion was reduced. It lasted up to 19 days in chronic studies, was not abolished by carotid sinus denervation nor with beta receptor blockade, but was absent after removal of brachiocephalic artery constriction (BCAC).
L. N. Cothran, M. S. Holder
openaire +3 more sources
Hypertension was produced in anesthetized and conscious dogs when cerebral perfusion was reduced. It lasted up to 19 days in chronic studies, was not abolished by carotid sinus denervation nor with beta receptor blockade, but was absent after removal of brachiocephalic artery constriction (BCAC).
L. N. Cothran, M. S. Holder
openaire +3 more sources
Purinergic signalling in brain ischemia
Neuropharmacology, 2016Ischemia is a multifactorial pathology characterized by different events evolving in the time. After ischemia a primary damage due to the early massive increase of extracellular glutamate is followed by activation of resident immune cells, i.e microglia, and production or activation of inflammation mediators.
PEDATA, FELICITA +6 more
openaire +3 more sources