Results 91 to 100 of about 34,869 (221)

New Aspects of Thromboangiitis obliterans (von Winiwarter-Buerger's Disease) [PDF]

, 1984
The existence of thromboangiitis obliterans as a clinical entity has been a matter of debate for many years. In contrast to other immunovasculitides there is no organ involvement while peripheral vessels are affected.
Reuther, R., Krause, Klaus-Henning, Kessler, C., Berlit, Peter   +3 more
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Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Agmatina, um candidato à adjuvante da farmacoterapia da depressão: estudos in vitro e in vivo [PDF]

, 2014
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-graduação em Bioquímica, Florianópolis, 2014A agmatina é um neuromodulador, cuja atividade antidepressiva tem sido mostrada tanto em ensaios pré ...
Freitas, Andiara Espíndola de
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Risk of hemorrhagic stroke in warfarin‐treated patients following heart valve replacement: Findings from the MAGPIE study

Ibrain, EarlyView.
Among 568 mechanical heart valve replacement patients in Bangladesh, hemorrhagic stroke occurred in 4.4% with 52% mortality. Severe pulmonary hypertension increased risk 4.4‐fold, and warfarin therapy ≥104 months nearly doubled the risk, highlighting the need for long‐term risk monitoring in anticoagulated valve patients.
Dipannita Adhikary, Md. Abdullah Yusuf, AM Nayeem Parvez, Sheikh M. B. Faruque, Santo Barman, Adneen Moureen, Luke J. Rogers, Aziz Momin, Venkatachalam Chandrasekaran, Asit B. Adhikary, Redoy Ranjan   +10 more
wiley   +1 more source

Avaliação farmacológica de uma fração rica em proantocianidinas obtida da Croton celtidifolius sobre o sistema nervoso central e em um modelo animal da doença de Parkinson [PDF]

, 2010
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2010No presente estudo investigamos as possíveis propriedades psicofarmacológicas e neuroprotetoras ...
Moreira, Eduardo Luiz Gasnhar
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Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source

Hydrogel‐based drug delivery systems for intracerebral hemorrhage with therapeutic advances and emerging roles of the bone–brain axis

Interdisciplinary Medicine, EarlyView.
Hydrogel‐based drug delivery systems offer a promising approach for treating intracerebral hemorrhage (ICH) by overcoming blood‐brain barrier limitations, enabling precise, sustained release of neuroprotective and anti‐inflammatory agents. These systems enhance treatment efficacy, but challenges remain in biosafety, drug penetration, and scalability ...
Haojun Shi, Min Chen, Yisheng Chen, MengYao Li, Jiale Ma, Zuozhen Yin, Li Wu, YangBao Miao, Zemin Ou, Ke Wu, Zhijie Xu, Lizhi Li, Shaocong Zhao, Shiwei He, Bin Huang, Guanwen He, Guanghui Wu, John H. Zhang, Liang Shi   +18 more
wiley   +1 more source

From regulatory mechanisms to cutting‐edge applications: Research progress of ultrasound, electrical, magnetic, and optical stimulation in neural modulation

Journal of Intelligent Medicine, EarlyView.
Abstract In recent years, the clinical treatment and symptom management of neurological disorders have faced significant challenges due to the high complexity of the nervous system's structure and function. Against this backdrop, physical stimulation techniques have emerged as a vital complementary approach to traditional pharmacological treatments and
Wanying Li, Liqun Chen
wiley   +1 more source

Management of Absent Upper Esophageal Sphincter Opening After Neurological Injury

The Laryngoscope, EarlyView.
This study evaluated the effects of swallowing therapy and cricopharyngeus (CP) muscle surgery on upper esophageal sphincter (UES) opening, oral intake, and airway protection in patients with absent UES opening following neurological injury. CP‐targeted surgeries were associated with improved bolus passage and oral intake, but persistent aspiration ...
Radhika Rawat, Cyrus W. Abrahamson, Kelly Rogers, Jonelyn Langenstein, Jaymie Bromfield, Arjun Seth, James A. Burns, Andrew P. Stein   +7 more
wiley   +1 more source

A PROSPECTIVE-STUDY OF CEREBRAL-ISCHEMIA IN THE YOUNG - ANALYSIS OF PATHOGENIC DETERMINANTS

, 1993
Background and Purpose: The etiology of stroke in the young is different from that in older patients and remains unknown in almost one third of the cases. To gain further insight into both pathogenic and etiologic determinants, we prospectively studied a
MARINI, Carmine, FERRANTI E, FRONTONI M, PRENCIPE M, CAROLEI, ANTONIO, FIESCHI C, AND NRC STUDY GROUP   +6 more
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