Results 91 to 100 of about 268,662 (315)

Modulation of habenular and nucleus accumbens functional connectivity by ketamine in major depression

Brain and Behavior
Introduction Major depressive disorder (MDD) is associated with dysfunctional reward processing, which involves functional circuitry of the habenula (Hb) and nucleus accumbens (NAc).
Brandon Taraku, Joana R. Loureiro, Ashish K. Sahib, Artemis Zavaliangos‐Petropulu, Noor Al‐Sharif, Amber M. Leaver, Benjamin Wade, Shantanu Joshi, Roger P. Woods, Randall Espinoza, Katherine L. Narr   +10 more
doaj   +1 more source

Subcortical electrophysiological activity is detectable with high-density EEG source imaging

Nature Communications, 2019
Electroencephalography (EEG) allows the measurement of electrical signals associated with brain activity, but it is unclear if EEG can accurately measure subcortical activity.
Martin Seeber, Lucia-Manuela Cantonas, Mauritius Hoevels, Thibaut Sesia, Veerle Visser-Vandewalle, Christoph M. Michel   +5 more
doaj   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

ACTIVATION OF ASTROCYTES DURING EPILEPTOGENESIS RESTORES ALTERATIONS IN BRAIN GLUCOSE METABOLISM

IBRO Neuroscience Reports, 2023
Nira Hernández Martín, Pablo Bascuñana, Rubén Fernández De La Rosa, Luis García-García, Eduardo Martín, M.A. Pozo   +5 more
doaj   +1 more source

Mapping the Structural Determinants Required for AAVrh.10 Transport across the Blood-Brain Barrier [PDF]

, 2017
Blake H. Albright, Claire M. Storey, Giridhar Murlidharan, Ruth M. Castellanos Rivera, Garrett E. Berry, Victoria J. Madigan, Aravind Asokan   +6 more
openalex   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source

Worldwide brain-mapping project sparks excitement — and concern [PDF]

, 2016
Sara Reardon
openalex   +1 more source

Brain-Wide Mapping of Water Flow Perception in Zebrafish [PDF]

, 2020
Gilles Vanwalleghem, Kevin Schuster, Michael A. Taylor, Itia A. Favre‐Bulle, Ethan K. Scott   +4 more
openalex   +1 more source

Mapping human brain organoids on a spatial atlas [PDF]

, 2021
Yuki Miura, Sergiu P. Pașca
openalex   +1 more source