Results 91 to 100 of about 888,532 (366)

A comparison of resting state functional magnetic resonance imaging to invasive electrocortical stimulation for sensorimotor mapping in pediatric patients [PDF]

open access: yes, 2019
Localizing neurologic function within the brain remains a significant challenge in clinical neurosurgery. Invasive mapping with direct electrocortical stimulation currently is the clinical gold standard but is impractical in young or cognitively delayed ...
Hacker, Carl D   +7 more
core   +2 more sources

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

Applications of fMRI for Brain Mapping [PDF]

open access: yesarXiv, 2012
Brain-mapping techniques have proven to be vital in understanding the molecular, cellular, and functional mechanisms of the brain. Normal anatomical imaging can provide structural information on certain abnormalities in the brain. However there are many neurological disorders for which only structure studies are not sufficient.
arxiv  

Brain Visualization in Java3D [PDF]

open access: yes, 2004
BrainJ3D is a cross-platform Java/Java3D software toolkit for processing and visualizing brain imaging data, which 1) contains general purpose tools for reconstructing, mapping and visualizing integrated structural and functional images and 2) leverages ...
Brinkley, James F   +2 more
core   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Prosopagnosia and the role of face-sensitive areas in race perception

open access: yesScientific Reports
Race is rapidly and effortlessly extracted from faces. Previous fMRI studies have reported race-related modulations in the bilateral Fusiform Face Areas (FFAs) and Occipital Face Areas (OFAs) during the categorization of faces by race.
Pauline Schaller   +4 more
doaj   +1 more source

Quantifying mesoscale neuroanatomy using X-ray microtomography [PDF]

open access: yesarXiv, 2016
Methods for resolving the 3D microstructure of the brain typically start by thinly slicing and staining the brain, and then imaging each individual section with visible light photons or electrons. In contrast, X-rays can be used to image thick samples, providing a rapid approach for producing large 3D brain maps without sectioning.
arxiv  

Brain Structural Saliency Over The Ages [PDF]

open access: yesarXiv, 2022
Brain Age (BA) estimation via Deep Learning has become a strong and reliable bio-marker for brain health, but the black-box nature of Neural Networks does not easily allow insight into the features of brain ageing.We trained a ResNet model as a BA regressor on T1 structural MRI volumes from a small cross-sectional cohort of 524 individuals. Using Layer-
arxiv  

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Ten Years of BrainAGE as a Neuroimaging Biomarker of Brain Aging: What Insights Have We Gained?

open access: yesFrontiers in Neurology, 2019
With the aging population, prevalence of neurodegenerative diseases is increasing, thus placing a growing burden on individuals and the whole society.
Katja Franke   +2 more
doaj   +1 more source

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