Results 141 to 150 of about 3,164,098 (302)

Modeling Progressive Brain Volume Losses in Chronic Moderate Severe Traumatic Brain Injury: Extensive, but Attenuating

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progressive brain atrophy has now been widely observed in the chronic stages of moderate–severe traumatic brain injury (msTBI), but there is only coarse information regarding its prevalence and magnitude, and whether rate of atrophy accelerates or attenuates across time. We examined these questions in a Canadian inception cohort from
Robin E. A. Green, Brenda Colella, Alana Changoor, David J. Mikulis, Adrienne Li, Kadeen Johns, Georges A. Monette   +6 more
wiley   +1 more source

Dynamics of Brain Connectivity in Relation to Glucose Metabolism: A Multimodal Study with rs-fMRI and [18F]FDG-PET

reservedThis study explores the dynamic states of functional brain connectivity and their relationship with glucose metabolism. A multimodal approach integrating resting-state functional MRI (rs-fMRI) and [18F]FDG-PET was used to investigate how temporal
TOMASI, SARA
core  

Nationwide Survey of Association Between Fever and Epileptic Seizure in CDKL5 Deficiency Disorder Revealed Therapeutic Implications

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective CDKL5 deficiency disorder (CDD) is a rare, severe developmental and epileptic encephalopathy. There is a pressing need to develop effective and sustainable therapeutic strategies. We aimed to investigate the causal association between febrile episodes and epileptic seizures for therapeutic implications in CDD patients.
Siyi Wang, Jialin Du, Jinghui Liu, Dongmei Hu, Hongxin Wang, Xiaoxiao Man, Lehong Gao, Shimin Hu, Xianghong Meng, Hongyang Zhao, Minjing Hu, Yingxue Yang, Zhiqi Xiong, Liankun Ren   +13 more
wiley   +1 more source

Metabolic and Fluid Biomarkers Support Microglia Activation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis is an incurable neurodegenerative disease involving motor neuron degeneration and metabolic and immune dysfunction. We combined clinical data, cerebrospinal fluid biomarkers and fluorodeoxyglucose positron emission tomography with magnetic resonance imaging to investigate the role of reactive microglia in disease ...
Matteo Zanovello, Francesca Serani, Alen Bebeti, Federica Paredi, Giulia Quadrio, Andrea Fortuna, Giacomo Maria Minicuci, Elena Pegoraro, Annachiara Cagnin, Diego Cecchin, Gianni Sorarù   +10 more
wiley   +1 more source

Utility of the APE2 Score as a Diagnostic Tool for Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To retrospectively evaluate the diagnostic performance of the Antibody Prevalence in Epilepsy and Encephalopathy (APE2) score relative to clinician‐adjudicated autoimmune encephalitis (AE) and the Graus criteria in a tertiary neuroimmunology referral cohort, including antibody‐negative AE.
Bijoya Basu, Sophia F. Damman, Samhitha M. Rai, Hesham Abboud   +3 more
wiley   +1 more source

Effect of hypoxia on brain energy metabolism during aging

, 1986
Because of the high heterogeneity of the brain, the characterization of various subcellular fractions from different brain areas is an important step forward in the development of the knowledge on the hypoxia induced changes of the brain metabolism ...
CURTI, DANIELA, BENZI, GIAN MARTINO, MARZATICO, FULVIO, DAGANI, FIORENZO   +3 more
core  

Energy paradox in REM sleep: balancing supply and consumption in brain metabolism. [PDF]

Commun Biol
Takahashi Y, Ikoma Y, Matsui K.
europepmc   +1 more source

Subjective Cognitive Concerns and Cognitive Trajectories in Parkinson's Disease: Biomarker Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the relationship of subjective cognitive concerns (SCC) with biomarkers of Alzheimer's disease (AD), neurodegeneration, and Parkinson's disease (PD) and domain‐specific cognitive trajectories among cognitively unimpaired persons with de novo PD. Method Cognitively unimpaired participants with SCC (n = 294) and without SCC (
Francesca V. Lopez, Fareshte Erani, Katherine J. Bangen, David G. Coughlin, Douglas Galasko, Kelsey R. Thomas   +5 more
wiley   +1 more source

Brain Glucose-metabolism in Striatonigral Degeneration - a Pet Study

, 1988
Brain Glucose-metabolism in Striatonigral Degeneration - a Pet ...
European Nuclear Medicine Congress, Goffinet, André, Laterre, Emile-Christian, Cogneau, M., Francart, J., Bol, Anne, De Volder, Anne, Michel, Christian   +7 more
core  

Overnight sleep features and next-morning brain metabolism in older adults. [PDF]

Sleep Med
Carvalho DZ, Adolf J, Kremen V, McCarter SJ, St Louis EK, Przybelski SA, Liu K, Jones DT, Petersen RC, Jack CR, Lowe VJ, Varga AW, Somers VK, Graff-Radford J, Grinberg LT, Boeve BF, Worrell GA, Vemuri P.   +17 more
europepmc   +1 more source