Results 191 to 200 of about 3,164,098 (302)

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

A targeted evidence map and meta-analysis of brain metabolism differences and brain-based diagnostic classifier performance across psychiatric disorders

This project will conduct a targeted evidence map and exploratory meta-analytic synthesis embedded within a broader conceptual manuscript. The purpose will be to compare two diagnosis-level evidence streams across selected psychiatric disorders: brain ...
Bita Shariatpanahi, Hamidreza Jamalabadi, Mina Kheirkhah, Stefan G. Hofmann   +3 more
core  

Assessment of early-phase [¹⁸F]florbetaben images as a proxy for brain metabolism in mouse models of Alzheimer's disease. [PDF]

J Cereb Blood Flow Metab
Gröger R, Englert AL, Lalia M, de Weerd L, Rovere M, Kunze L, Palumbo G, Wind-Mark K, Fixemer S, Roemer-Cassiano SN, Franzmeier N, Höglinger G, Zwergal A, Tahirovic S, Werner RA, Brendel M, Gnörich J.   +16 more
europepmc   +1 more source

Hemocompatible Glycogen‐Tissue Plasminogen Activator Complexes for Enhanced Blood Clot Dissolution

Advanced Healthcare Materials, EarlyView.
Glycogen–heparin‐cRGD nanoparticles enable targeted delivery of tissue plasminogen activator (tPA) to thrombi through activated platelet recognition. The hemocompatible hybrids minimize interactions with blood and immune cells while retaining enzymatic biodegradability.
Nadiia Davydiuk, Vaidehi Londhe, Susanne Boye, Martin Müller, Carsten Werner, Manfred F. Maitz, Quinn A. Besford   +6 more
wiley   +1 more source

Exploring the interplay between mitochondrial metabolism and presynaptic plasticity in early aging Drosophila brain

EXPLORING THE INTERPLAY BETWEEN MITOCHONDRIAL METABOLISM AND PRESYNAPTIC PLASTICITY IN EARLY AGING DROSOPHILA BRAIN Exploring the interplay between mitochondrial metabolism and presynaptic plasticity in early aging Drosophila brain / Fei, Lu (Rights ...
Fei, Lu
core  

A short photoperiod alters brain metabolism and cold resistance in Drosophila melanogaster. [PDF]

Sci Rep
Sapre M, Hovhanyan A, Schmitz W, Deppisch P, Gera J, Mueller MJ, Menegazzi P, Fekete A, Helfrich-Förster C.   +8 more
europepmc   +1 more source

Microgels Enable iPSCs to Assemble, Expand, and Differentiate Into Organoids—From Sizable to High‐Throughput

Advanced Materials, EarlyView.
A chemically defined PEG‐based microgel platform enables scalable, reproducible production of three‐dimensional microgel‐iPSC constructs in multiple sizes. The system is compatible with high‐throughput automation and supports human iPSC expansion and differentiation within a single construct, including directed differentiation into cardiac organoids ...
Laura Klasen, Matthias Mork, Ramin Nasehi, Vasudha Turuvekere Krishnamurthy, Kira Zeevaert, Aaron Babendreyer, Jacopo Di Russo, Wolfgang Wagner, Laura De Laporte   +8 more
wiley   +1 more source

Time-dependent biphasic alterations in brain metabolism following chronic ketamine exposure in mice. [PDF]

Front Pharmacol
Lim SH, Choi YS, Kim E, Kim CH, Song HT.
europepmc   +1 more source

Charge‐Reversed Lipid Nanoparticles Enable Encapsulation of Pt2L4 Nanocages for In vivo Anti‐Cancer Treatment

Advanced Materials, EarlyView.
Charge‐reversed lipid nanoparticles (revLNPs) enable efficient encapsulation and delivery of cationic Pt2L4 nanocages. Encapsulation preserves potent anticancer activity while improving circulation, reducing vascular leakage, and promoting favorable biodistribution in vivo.
Renzo A. Knol, Bochuan Hu, Eduard O. Bobylev, Martina Farber, Petrus C. M. Laan, Thomas J. F. Kock, Bauke Fontein, Johanna Erbani, Oscar Escalona‐Rayo, Seline S. Roose, Tom Keijer, Gabriel Forn‐Cuní, B. Ewa Snaar‐Jagalska, Leila Akkari, Joost N. H. Reek, Alexander Kros, Dennis Aschmann   +16 more
wiley   +1 more source

COVID-19 Fog Symptoms Are Associated with Brain Metabolism and Platelet-to-Lymphocyte Ratio-A Cross-Sectional Analysis of the COVMENT Trial Baseline Data. [PDF]

J Clin Med
Lubas A, Bryłowska J, Grzywacz A, Włochacz B, Giżewska A, Dziuk M, Klimkiewicz A, Klimkiewicz J.   +7 more
europepmc   +1 more source