Results 91 to 100 of about 182,203 (309)

A Rare Presentation: Leptomeningeal Disease Involving the Left Cerebellar Hemisphere and Lumbosacral Region in Breast Cancer

Pakistan Journal of Medicine and Dentistry
Leptomeningeal disease (LMD) is a rare condition that occurs in fewer than 5% of breast cancer patients. In certain instances, individuals exhibit symptoms of LMD when initially diagnosed.
Rida Aziz, Arifa Shahzadi, Hamza Tanzeel, Ayesha Siddiqa, Areeba Aziz   +4 more
doaj   +1 more source

Similarities vs. key discrepancy between tuberculosis and cancer [PDF]

arXiv, 2018
In 2015 in the United States 612,000 persons died from cancer whereas only 470 died from tuberculosis (TB), a disease which was the main cause of death around 1900. How can one explain such a key discrepancy in treatment progress? A statistical comparison between TB and cancer will give some clues.
arxiv  

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Study on diagnosis and differential diagnosis of common tumors in the posterior fossa of children based on diffusion-weighted imaging

Chinese Journal of Contemporary Neurology and Neurosurgery
Objective To investigate the imaging diagnosis and differential diagnosis methods for common tumors in the posterior fossa of children, and to propose a flow chart for the diagnosis of common tumors in the posterior fossa of children based on the limited
DING Xing-hua, ZHU Ying-feng, ZHANG Chao, ZHU Yi-qian, ZHANG Rong   +4 more
doaj   +1 more source

A potential tumor suppressor role of PLK2 in glioblastoma

FEBS Open Bio, EarlyView.
PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia, Peirui Wang, Hua Xiao, Qishan Ran, Yan Li, Shengtao Yao   +5 more
wiley   +1 more source

The importance of basic and translational research in caring for children with malignant solid tumors in Latin America

Revista Panamericana de Salud Pública
Objective. Basic and translational research in pediatric cancer are essential to improve patient care. To critically assess the developments achieved in these areas in Latin America, we systematically reviewed information published between 2013 and 2023.
María Belen Cancela, Milagros Dinardi, Rosario Aschero, Santiago Zugbi, Guillermo Chantada, Lorena Baroni, Paula Schaiquevich   +6 more
doaj   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Preoperative Cortical Mapping for Brain Tumor Surgery Using Navigated Transcranial Stimulation: Analysis of Accuracy

Brain Sciences
Transcranial magnetic stimulation (TMS) represents a distinctive technique for non-invasive brain stimulation. Recent advancements in image processing have enabled the enhancement of TMS by integrating magnetic resonance imaging (MRI) modalities with TMS
Wellingson Silva Paiva, Erich Talamoni Fonoff, Rhuann Pontes dos Santos Silva, Lucas Schiavao, André Russowsky Brunoni, César Cimonari de Almeida, Carlos Carlotti Júnior   +6 more
doaj   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Microsurgical ressection for parasagittal meningiomas with preservation of the parasagittal sinus and excelent neurovascular control Ressecção microcirúrgica dos meningiomas parasagitais com excelente controle vascular e preservação do seio longitudinal superior

Arquivos de Neuro-Psiquiatria, 2013
Objective: It was to observe whether a microsurgical gross total removal (GTR) of a parasagittal meningioma (PSM) outside the sinus is a safe and efficient procedure. Method: We identify 58 parasagittal meningiomas patients.
José Carlos Lynch, Hugo Schiavini, Cleber Bomfim, Joelton Fernandes Fonseca, Celestino Pereira   +4 more
doaj