Results 81 to 90 of about 5,034,832 (289)
, 2023 Primary CNS neoplasms are responsible for considerable mortality and morbidity, and many therapies directed at primary brain tumors have proven unsuccessful despite their success in preclinical studies.
Anita L. Kalluri +5 more
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IJU Case ReportsIntroduction Patients with metastatic renal cell carcinoma have a poor prognosis and its specific pathogenesis remains unelucidated. Case presentation At 78 years of age, a Japanese male patient was diagnosed with metastatic renal cell carcinoma (cT3N2M1
Daisuke Matsumoto +9 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Pathology of Intracranial Neoplasms
, 1999 This article discusses the gross and microscopic pathology of intracranial neoplasms. Primary intracranial neoplasms include tumors of the brain parenchyma; meninges; and rest of mesenchymal, epithelial, and germ cell derivation.
Coons, S. W., Ashby, Lynn S.
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, 2018 The video in this chapter discusses neoplasms of the central nervous system (CNS), including metastatic tumors, common primary brain tumors (pediatric astrocytoma, pediatric medulloblastoma, adult meningioma, and adult glioblastoma), as well as pituitary
Tracey Milligan, Tamara Kaplan
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Unlocking the Enigma of Cotard’s Syndrome: A Narrative Review of its Clinical Manifestations and Therapeutic Strategies [PDF]
Journal of Clinical and Diagnostic ResearchThis narrative review explores Cotard’s Syndrome (CS), a rare psychiatric condition characterised by delusions of death or non-existence, originally described by Jules Cotard in 1880.
Mudit Saxena +3 more
doaj +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Neuroplasticity and brain neoplasms [PDF]
Neuroplasticity is the ability of the brain to reorganize its networks to adapt to changes in neural surroundings. It is an important component of learning and memory, but it is also critical in the process of tissue recovery after brain injury.
Klarin, Vanja, Krklec, Marko
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