Results 1 to 10 of about 103,286 (345)

Meningioma: A Review of Epidemiology, Pathology, Diagnosis, Treatment, and Future Directions

Biomedicines, 2021
Meningiomas are the most common intracranial tumor, making up more than a third of all primary central nervous system (CNS) tumors. They are mostly benign tumors that can be observed or preferentially treated with gross total resection that provides good
Christian Ogasawara
exaly   +2 more sources

Comprehensive Molecular Profiling Identifies FOXM1 as a Key Transcription Factor for Meningioma Proliferation

Cell Reports, 2018
Summary: Meningioma is the most common primary intracranial tumor, but the molecular drivers of aggressive meningioma are incompletely understood. Using 280 human meningioma samples and RNA sequencing, immunohistochemistry, whole-exome sequencing, DNA ...
Harish N. Vasudevan, Steve E. Braunstein, Joanna J. Phillips, Melike Pekmezci, Bryan A. Tomlin, Ashley Wu, Gerald F. Reis, Stephen T. Magill, Jie Zhang, Felix Y. Feng, Theodore Nicholaides, Susan M. Chang, Penny K. Sneed, Michael W. McDermott, Mitchel S. Berger, Arie Perry, David R. Raleigh   +16 more
doaj   +2 more sources

Clinical Significance of Somatostatin Receptor (SSTR) 2 in Meningioma

Frontiers in Oncology, 2020
Somatostatin receptor (SSTR) 2, widely expressed in meningioma, is a G-protein-coupled receptor and can be activated by somatostatin or its synthetic analogs.
Wei Wu, Yunxiang Zhou, Yali Wang, Lihong Liu, Jianyao Lou, Yongchuan Deng, Peng Zhao, Anwen Shao   +7 more
doaj   +2 more sources

The ASNR-MICCAI Brain Tumor Segmentation (BraTS) Challenge 2023: Intracranial Meningioma [PDF]

arXiv.org, 2023
Meningiomas are the most common primary intracranial tumor in adults and can be associated with significant morbidity and mortality. Radiologists, neurosurgeons, neuro-oncologists, and radiation oncologists rely on multiparametric MRI (mpMRI) for ...
D. LaBella, M. Adewole, M. Alonso-Basanta, T. Altes, S. Anwar, U. Baid, T. Bergquist, R. Bhalerao, Sully Chen, Verena Chung, G. Conte, Farouk Dako, James A. Eddy, I. Ezhov, D. Godfrey, Fathi Hilal, A. Familiar, K. Farahani, J. E. Iglesias, Zhifan Jiang, Elaine Johanson, A. Kazerooni, C. Kent, J. Kirkpatrick, F. Kofler, K. Leemput, H. Li, Xinyang Liu, Aria Mahtabfar, Shan McBurney-Lin, Ryan McLean, Zeke Meier, A. Moawad, John Mongan, Pierre Nedelec, Maxence Pajot, M. Piraud, Arif Rashid, Z. Reitman, R. Shinohara, Yury Velichko, C. Wang, P. Warman, Walter F. Wiggins, M. Aboian, Jake Albrecht, U. Anazodo, S. Bakas, A. Flanders, A. Janas, Goldey Khanna, M. Linguraru, Bjoern H Menze, A. Nada, A. Rauschecker, J. Rudie, N. Tahon, J. Villanueva-Meyer, Benedikt Wiestler, E. Calabrese   +59 more
semanticscholar   +1 more source

Meningioma DNA methylation groups identify biological drivers and therapeutic vulnerabilities

Nature Genetics, 2022
Meningiomas are the most common primary intracranial tumors. There are no effective medical therapies for meningioma patients, and new treatments have been encumbered by limited understanding of meningioma biology.
A. Choudhury, S. Magill, C. Eaton, B. Prager, William C. Chen, M. Cady, K. Seo, C. Lucas, T. Casey-Clyde, H. Vasudevan, S. Liu, J. Villanueva-Meyer, T. Lam, J. Pu, L. Li, G. Leung, D. Swaney, Michael Zhang, J. Chan, Zhixin Qiu, Michael V. Martin, M. Susko, S. Braunstein, N. Bush, J. Schulte, N. Butowski, P. Sneed, M. Berger, N. Krogan, A. Perry, J. Phillips, D. Solomon, J. Costello, M. McDermott, Jeremy N. Rich, D. Raleigh   +35 more
semanticscholar   +1 more source

Study of Clinico-Pathological Spectrum of Meningioma with WHO Grading

National Journal of Laboratory Medicine, 2023
Introduction: Meningiomas are the most frequent non glial primary Central Nervous System (CNS) tumour. Several histopathological patterns of meningiomas are classified and graded.
Jyothika Kumar, Poornima V Kamatar, Vidhisha Athanikar   +2 more
doaj   +1 more source

The potential involvement of E-cadherin and beta-catenins in meningioma. [PDF]

PLoS ONE, 2010
OBJECTIVE: To investigate the potential involvements of E-cadherin and beta-catenin in meningioma. METHODS: Immunohistochemistry staining was performed on samples from patients with meningioma.
Keiyu Zhou, Guangtao Wang, Yirong Wang, Hanghuang Jin, Shuxu Yang, Chibo Liu   +5 more
doaj   +1 more source

Targeted gene expression profiling predicts meningioma outcomes and radiotherapy responses

Nature Medicine, 2023
Surgery is the mainstay of treatment for meningioma, the most common primary intracranial tumor, but improvements in meningioma risk stratification are needed and indications for postoperative radiotherapy are controversial.
William C. Chen, A. Choudhury, Mark W. Youngblood, Mei-Yin C. Polley, Calixto-Hope G. Lucas, K. Mirchia, Sybren L. N. Maas, Abigail K. Suwala, M. Won, James C. Bayley, A. Harmanci, A. Harmanci, Tiemo J. Klisch, M. P. Nguyen, H. Vasudevan, Kathleen McCortney, Theresa J. Yu, Varun Bhave, Tai-Chung Lam, J. Pu, L. Li, G. Leung, Jason W. Chan, H. Perlow, J. Palmer, C. Haberler, A. Berghoff, M. Preusser, T. Nicolaides, C. Mawrin, S. Agnihotri, A. Resnick, Brian R. Rood, Jessica J. Chew, Jacob S. Young, L. Boreta, S. Braunstein, J. Schulte, N. Butowski, S. Santagata, D. Spetzler, N. Bush, J. Villanueva-Meyer, James P. Chandler, D. Solomon, C. Rogers, S. Pugh, Minesh P. Mehta, P. Sneed, Mitchell S. Berger, C. Horbinski, M. W. McDermott, A. Perry, W. Bi, Akash J. Patel, F. Sahm, S. Magill, D. Raleigh   +57 more
semanticscholar   +1 more source

Association between tumor size and peritumoral brain edema in patients with convexity and parasagittal meningiomas

PLoS ONE, 2021
Background and purpose Peritumoral brain edema (PTBE) is a common complication in meningioma and disruption of the tumor-brain barrier in meningioma is crucial for PTBE formation.
Chansub Shin, Jae Min Kim, Jin Hwan Cheong, Je Il Ryu, Yu Deok Won, Yong Ko, Myung-Hoon Han   +6 more
doaj   +2 more sources

Integrated Molecular-Morphologic Meningioma Classification: A Multicenter Retrospective Analysis, Retrospectively and Prospectively Validated

Journal of Clinical Oncology, 2021
PURPOSE Meningiomas are the most frequent primary intracranial tumors. Patient outcome varies widely from benign to highly aggressive, ultimately fatal courses.
S. L. N. Maas, D. Stichel, T. Hielscher, P. Sievers, A. Berghoff, D. Schrimpf, M. Sill, P. Euskirchen, C. Blume, Areeba Patel, H. Dogan, D. Reuss, H. Dohmen, M. Stein, A. Reinhardt, A. Suwala, A. Wefers, P. Baumgarten, F. Ricklefs, E. Rushing, M. Bewerunge-Hudler, R. Ketter, J. Schittenhelm, Z. Jaunmuktane, S. Leu, F. Greenway, L. Bridges, T. Jones, Conor Grady, J. Serrano, J. Golfinos, C. Sen, C. Mawrin, C. Jungk, D. Hänggi, M. Westphal, K. Lamszus, N. Etminan, G. Jungwirth, C. Herold‐Mende, A. Unterberg, P. Harter, H. Wirsching, M. Neidert, M. Ratliff, M. Plattén, M. Snuderl, K. Aldape, S. Brandner, J. Hench, S. Frank, S. Pfister, David C. Jones, G. Reifenberger, T. Acker, W. Wick, M. Weller, M. Preusser, A. von Deimling, F. Sahm   +59 more
semanticscholar   +1 more source