Results 91 to 100 of about 2,078,004 (301)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Examining the frequency of brain tumors in Porsina Hospital in Rasht based on pathological and surgical characteristics

Journal of Current Oncology and Medical Sciences
Introduction: Understanding the frequency of malignant and non-malignant brain tumors is crucial for understanding disease causes. Factors such as histological type, age of diagnosis, sex, and race are considered. Identifying risk factors such as allergy,
Seyed Amir Reza Shekarian, Ali Akbar Samadani, Kourosh Delpasand, Ali Ashraf, Zohreh Tymori, Paridokht Karimiyan   +5 more
doaj  

The dawn here is quiet: a guided reading in shout

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
DOI：10.3969/j.issn.1672⁃6731.2020.04 ...
Song⁃tao QI
doaj  

Quality of Life in Brain Cancer: Clinical Validation of the Mexican-Spanish Version of the EORTC QLQ-BN20 Questionnaire

Frontiers in Neurology, 2019
Background: Overall survival (OS) of patients with Brain Cancer (BC) is slowly increasing. The disease itself and its treatments deeply impact patient Health-related quality of life (HRQL). Therefore, valid and reliable instruments are needed.
Bernardo Cacho-Díaz, Nydia A. Lorenzana-Mendoza, Luis F. Oñate-Ocaña   +2 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Brain differences between persistent and remitted attention deficit hyperactivity disorder [PDF]

, 2014
Previous resting state studies examining the brain basis of attention deficit hyperactivity disorder have not distinguished between patients who persist versus those who remit from the diagnosis as adults.
Kagan, Elana, Spencer, Thomas, Biederman, Joseph, Brown, Ariel, Kotte, Amelia, Gabrieli, Susan, Mattfeld, Aaron T., Gabrieli, John D. E.   +7 more
core   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Paediatric traumatic Brain Injury: The relationship between Intracranial Pressure and Brain Oxygenation [PDF]

, 2009
Introduction: Intracranial pressure (ICP) monitoring is a cornerstone of care for patients with severe traumatic brain injury (TBI). The primary goal of ICP treatment is to preserve brain oxygenation, and since brain oxygenation is usually not measured ...
Rohlwink, Ursula Karin
core   +1 more source

Comparative Efficacy and Safety of Immunotherapy on Non–Small Cell Lung Cancer Patients With Brain Metastases: A Systematic Review and Network Meta‐Analysis

The Clinical Respiratory Journal
Background Growing evidence suggests that immunotherapy has a positive effect on non–small cell lung cancer (NSCLC) patients with brain metastases (BMs). However, it remains unclear which type of immunotherapy is more efficient.
Tianyi Lyu, Bo Sun, Daowen Yang, Xirui Zhao, Ruoshui Wang, Xinyang Shu, Demin Li, Hong Chen   +7 more
doaj   +1 more source

Primary Central Nervous System B-Cell Lymphoma Presenting with Fluctuating Basal Ganglia and Cortical Lesions

Journal of the Belgian Society of Radiology
A 68-year-old woman presented with progressive hemiparesis and dysphagia, initially presumed to have subacute stroke. Serial MRI revealed fluctuating FLAIR hyperintensities and enhancing lesions in the basal ganglia and cortex, ultimately leading to the ...
Christophe Sonck, Jef Huyskens
doaj   +1 more source