Results 81 to 90 of about 213,449 (352)

Advances in the study of tumor markers for intracranial germ cell tumors

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
Intracranial germ cell tumors (ICGCTs) are highly heterogeneous tumors that tend to occur in children and adolescents, and their diagnosis and treatment strategies are closely related to their pathological components.
Lei HAN, Zi⁃jun HE, Lu⁃xiong FANG, Ye SONG   +3 more
doaj  

A Report On Brain Neoplasms in Two Canine Patients [PDF]

, 1965
During the past year two canine patients afflicted by brain neoplasms were admitted into the small animal clinic. These two particular neoplasms are representative of the brain tumors most commonly seen in the dog, namely the meningioma and ...
Froehlich, Robert
core   +2 more sources

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Hürthle cell carcinoma: current perspectives. [PDF]

, 2016
Hürthle cell carcinoma (HCC) can present either as a minimally invasive or as a widely invasive tumor. HCC generally has a more aggressive clinical behavior compared with the other differentiated thyroid cancers, and it is associated with a higher rate ...
Ahmadi, Sara, Jiang, Xiaoyin Sara, Sosa, Julie Ann, Stang, Michael   +3 more
core   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Imaging correlates of molecular signatures in oligodendrogliomas. [PDF]

, 2004
Molecular subsets of oligodendroglioma behave in biologically distinct ways. Their locations in the brain, rates of growth, and responses to therapy differ with their genotypes. Retrospectively, we inquired whether allelic loss of chromosomal arms 1p and
Betensky, Rebecca A, Cairncross, J Gregory, Forsyth, Peter A, Kachur, Edward, Lee, Donald H, Louis, David N, Megyesi, Joseph F, Mizoguchi, Masahiro, Okada, Yoshifumi, Sasaki, Hikaru, Zlatescu, Magdalena C   +10 more
core   +2 more sources

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Heterocyclic scaffolds as promising anticancer agents against tumours of the central nervous system: Exploring the scope of indole and carbazole derivatives [PDF]

, 2014
Tumours of the central nervous system are intrinsically more dangerous than tumours at other sites, and in particular, brain tumours are responsible for 3% of cancer deaths in the UK. Despite this, research into new therapies only receives 1% of national
Akinaga, Alliance for Clinical Trials in Oncology, Arakawa, Arakawa, Awada, Barraja, Behrens, Boutros, Bradlow, Brain Tumour Research, Butowski, Camoratto, Cavazos, Cephalon, Chalmers, Chan, Chin, Chinni, Chris Sherer, Cleary, Davis, de Cresci Braga Montelli, Dekker, Deslandes, Deslandes, Diebold, Dowlati, Eckhardt, Evans, Evans, Fabbro, Faul, Fine, Frydoonfar, Frydoonfar, Galanis, Gilbert, Graff, Grose, Horton, Howells, Hudkins, Hudson, Hug, Hurwitz, Iyer, Jaszfold-Howorko, Jiang, Jones-Bolin, Kalkunte, Kaneko, Kase, Kojiri, Kreisl, Kristjansdottir, Lal, Langevin, Le Mée, Leppänen, Lewis, Lin, Lozano, Luo, Léonce, Magedov, Mahboobi, Marshall, Meggio, Merchant, Miknyoczki, Miknyoczki, Milhon, Nachshon-Kedmi, Nakano, Nathan, Nathan, Nelson, Nettleton, Norris, Ohmichi, Overmeyer, Overmeyer, Parsons, Peck, Pfizer, Prabhu, Prudent, Pundir, Rampling, Robinson, Ronnstrand, Rowinsky, Ruggeri, Saif, Satyan, Shen, Siegel, Singh, Stark, Tanaka, Timothy J. Snape, Tolcher, Toullec, Trabbic, Tutsch, Vassal, Walter, Weitman, Weng, Wick, Wick, Williams, Yamada, Yamashita, Yoshinari, Yoshinari, Yoshinari, Zheng   +117 more
core   +1 more source

Interplay of integrins and selectins in metastasis

Molecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva, Ashot Nersisyan, Alexander Tonevitsky   +2 more
wiley   +1 more source

Physiopathological Aspects of Sellar Epidermoid Cyst Determining Endocrine Disturbances: A Case Report

Brazilian Neurosurgery, 2019
Epidermoid cysts (ECs) of the central nervous system (CNS) constitute benign circumscribed lesions that are more common in lateral than in midline sites.
Eduardo Cambruzzi, Nelson Pires Ferreira, Gabriel Barcellos, Pablo Fruet   +3 more
doaj   +1 more source