Results 101 to 110 of about 7,145,458 (289)

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

Brain Size and Intelligence in Man

open access: yesBrain, Behavior and Evolution, 2008
The relationship between brain size and intelligence was investigated in two ways. Cranial capacity was measured in people with known IQs. A very small correlation was found between cranial capacity and intelligence; but this was shown to be the result of the confounding effects of height.
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Brain and body size data.

open access: yes, 2013
Dataset of body size and brain size for insectivorous mammals used in the present analysis.
Patricia A. Holroyd (388825)   +4 more
core   +1 more source

Pheochromocytoma with Brain Metastasis: A Extremely Rare Case in Worldwide. [PDF]

open access: yes, 2018
Pheochromocytoma (PCC) is a neuroendocrine tumor that mainly arises from the medulla of the adrenal gland. Some PCCs become malignant and metastasize to other organs.
조윤성, 김세훈, 강석구
core   +1 more source

Brain Size or Brain Organization and Intelligence

open access: yesPediatric Neurology Briefs, 1998
The relationship of head size and intelligence quotient (IQ) to neuroanatomic similarities in young, healthy adult monozygotic (MZ) twins was examined using MRI and quantitative image analysis at the Department of Neurobiology, Harvard Medical School, Boston, MA.
openaire   +4 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

When larger brains do not have more neurons: Increased numbers of cells are compensated by decreased average cell size across mouse individuals

open access: yesFrontiers in Neuroanatomy, 2015
There is a strong trend toward increased brain size in mammalian evolution, with larger brains composed of more and larger neurons than smaller brains across species within each mammalian order.
Suzana eHerculano-Houzel   +3 more
doaj   +1 more source

Brain size varies with temperature in vertebrates

open access: yes, 2014
The tremendous variation in brain size among vertebrates has long been thought to be related to differences in species’ metabolic rates. Species with higher metabolic rates can supply more energy to support the relatively high cost of brain tissue.
James F Gillooly
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

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