Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay +13 more
wiley +1 more source
Increased brain size of the dwarf Channel Island fox (Urocyon littoralis) challenges "Island Syndrome" and suggests little evidence of domestication. [PDF]
PLoS OneSchoenberger KA, Wang X, Edmands S.
europepmc +1 more source
Using relative brain size as predictor variable: Serious pitfalls and solutions. [PDF]
Ecol Evol, 2022 Smeele SQ.
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source
The Relationship Between Relative Brain Size and Avoidance of Vehicular Collisions in Birds is Subtle. [PDF]
Zool StudZink RM, Buchanan BL.
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Drosophila CASK regulates brain size and neuronal morphogenesis, providing a genetic model of postnatal microcephaly suitable for drug discovery. [PDF]
Neural Dev, 2023 Tello JA, Jiang L, Zohar Y, Restifo LL.
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro +14 more
wiley +1 more source
Captivity alters behaviour but not seasonal brain size change in semi-naturally housed shrews. [PDF]
R Soc Open SciBaldoni C +13 more
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Sociality, ecology and developmental constraints predict variation in brain size across birds. [PDF]
J Evol Biol, 2023 Hardie JL, Cooney CR.
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T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ±
Sarah J. Wright +10 more
wiley +1 more source