Results 91 to 100 of about 922,631 (303)

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Tectal plate tumors Tumores da região tectal

Arquivos de Neuro-Psiquiatria, 2006
Tectal plate is a rare location for a tumor. Many papers have described different types of pathology arising in that location including tumors, vascular lesions, inflamatory and infectious processes.
Bruno C.R. Lázaro, José A. Landeiro
doaj   +1 more source

Neural Development: Brain stems [PDF]

Current Biology, 1995
The discovery of stem cells in adult nerve tissue makes the repair of brain damage a realistic possibility.
openaire   +2 more sources

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Lateral habenula astroglia modulate the potentiating antidepressant-like effects of bright light stimulation in intractable depression

Frontiers in Pharmacology
BackgroundBeside image vision, light plays a pivotal role in regulating diverse non-visual functions, including affective behaviors. Recently, bright light stimulation (BLS) was revealed to be beneficial for treating non-seasonal depression, although its
Sarah Delcourte, Amel Bouloufa, Renaud Rovera, Elie Brunet, Hiep D. Le, April E. Williams, Satchidananda Panda, Rihab Azmani, Olivier Raineteau, Ouria Dkhissi-Benyahya, Nasser Haddjeri   +10 more
doaj   +1 more source

Potenciais evocados auditivos de tronco encefálico por frequência específica e de estado estável na audiologia pediátrica: estudo de caso Frequency-specific and steady-state evoked auditory brainstem responses in pediatric audiology: case study

Revista da Sociedade Brasileira de Fonoaudiologia, 2009
Preconiza-se o diagnóstico até os três meses de idade em crianças com deficiência auditiva congênita. Após a etapa inicial de confirmação do diagnóstico, é necessário que se obtenha limiares precisos nas diferentes frequências, para que seja possível uma
Gabriela Ribeiro Ivo Rodrigues, Mabel Gonçalves Almeida, Dóris Ruth Lewis   +2 more
doaj   +1 more source

The cell of origin dictates the temporal course of neurofibromatosis-1 (Nf1) low-grade glioma formation. [PDF]

, 2017
Low-grade gliomas are one of the most common brain tumors in children, where they frequently form within the optic pathway (optic pathway gliomas; OPGs).
Castillon, Guillaume A, Cimino, Patrick J, Ellisman, Mark H, Gianino, Scott M, Gutmann, David H, Lee, Da Yong, Ma, Yu, Pan, Yuan, Solga, Anne C, Toonen, Joseph A   +9 more
core   +3 more sources

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Analysis of wave III of brain stem auditory evoked potential waveforms during microvascular decompression of cranial nerve VII for hemifacial spasm [PDF]

, 2014
INTRODUCTION:: Intraoperative monitoring of brain stem auditory evoked potential during microvascular decompression (MVD) prevent hearing loss (HL). Previous studies have shown that changes in wave III (wIII) are an early and sensitive sign of auditory ...
, Balaji Krishnaiah, Barker, Donald J. Crammond, Hatayama, James, Jannetta, Jeffrey R. Balzer, Lee, Little, Marneffe, Miguel E. Habeych, Parthasarathy D. Thirumala, Ramnarayan   +13 more
core   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source