Results 31 to 40 of about 5,394,222 (376)

Optogenetics and deep brain stimulation neurotechnologies [PDF]

, 2015
Brain neural network is composed of densely packed, intricately wired neurons whose activity patterns ultimately give rise to every behavior, thought, or emotion that we experience. Over the past decade, a novel neurotechnique, optogenetics that combines
A Berndt, A Berndt, A Priori, AA Kuhn, AA Kuhn, AS Chuong, B Sauer, B Wingeier, BY Chow, BY Chow, C Bamann, D Luo, D Oesterhelt, D Oesterhelt, D Williams, ES Boyden, EY Uc, F Zhang, F Zhang, G Foffani, G Miesenbock, G Nagel, J Cavanaugh, J Mobley, J Volkmann, J Wells, J Wietek, JG Bernstein, JG Bernstein, JG Bernstein, JL Spudich, JL Spudich, JO Dostrovsky, JZ Tsien, L Bekar, L Madisen, LA Gunaydin, M Weinberger, M Weinberger, MC Rodriguez-Oroz, MJ Lehmkuhle, ML Welter, MM Doroudchi, O Yizhar, P Brown, P Silberstein, R Levy, R Levy, R Levy, R Waehler, S Zhao, TW Chen, VC Anderson, X Han, X Han, X Han, X Han, X Han, X Liu   +58 more
core   +2 more sources

A unified connectomic target for deep brain stimulation in obsessive-compulsive disorder

Nature Communications, 2020
Multiple surgical targets for treating obsessive-compulsive disorder with deep brain stimulation (DBS) have been proposed. However, different targets may modulate the same neural network responsible for clinical improvement.
Ningfei Li, J. Baldermann, A. Kibleur, S. Treu, H. Akram, G. Elias, A. Boutet, A. Lozano, B. Al-Fatly, B. Strange, J. Barcia, L. Zrinzo, E. Joyce, S. Chabardès, V. Visser-Vandewalle, M. Polosan, J. Kuhn, A. Kühn, A. Horn   +18 more
semanticscholar   +1 more source

Towards a computational model for stimulation of the Pedunculopontine nucleus [PDF]

, 2009
The pedunculopontine nucleus (PPN) has recently been suggested as a new therapeutic target for deep brain stimulation (DBS) in patients suffering from Parkinson's disease, particularly those with severe gait and postural impairment [1].
Gils, Stephan A. van, Heida, Tjitske, Lourens, Marcel A.J., Meijer, Hil G.E.   +3 more
core   +4 more sources

Association between cognitive performance and cortical glucose metabolism in patients with mild Alzheimer's disease [PDF]

, 2005
Background: Neuronal and synaptic function in Alzheimer's disease (AD) is measured in vivo by glucose metabolism using positron emission tomography (PET). Objective: We hypothesized that neuronal activation as measured by PET is a more sensitive index of
A. Drzezga, A.L.W. Bokde, Baron JC, C. Born, Collins DL, G. Leinsinger, H. Hampel, H.-J. Moeller, Herholz K, Herscovitch P, Ibanez V, Ishii K, J. Thissen, Jueptner M, M. Schwaiger, McKhann G, Meltzer CC, Meltzer CC, Mentis MJ, Mentis MJ, P. Bartenstein, Pietrini P, Pietrini P, Pietrini P, Rapoport SI, S.J. Teipel, Sokoloff L, W. Dong   +27 more
core   +1 more source

ABS: Scanning Neural Networks for Back-doors by Artificial Brain Stimulation

Conference on Computer and Communications Security, 2019
This paper presents a technique to scan neural network based AI models to determine if they are trojaned. Pre-trained AI models may contain back-doors that are injected through training or by transforming inner neuron weights.
Yingqi Liu, Wen-Chuan Lee, Guanhong Tao, Shiqing Ma, Yousra Aafer, X. Zhang   +5 more
semanticscholar   +1 more source

Efficacy of non-invasive brain stimulation on cognitive functioning in brain disorders: a meta-analysis

Psychological Medicine, 2020
Background Cognition is commonly affected in brain disorders. Non-invasive brain stimulation (NIBS) may have procognitive effects, with high tolerability.
M. Begemann, B. Brand, B. Ćurčić-Blake, A. Aleman, I. Sommer   +4 more
semanticscholar   +1 more source

Vagus Nerve Stimulation Affects Pain Perception in Depressed Adults

Pain Research and Management, 2005
BACKGROUND: Previous research suggests that vagus nerve stimulation (VNS) affects pain perception in epilepsy patients, with acute VNS decreasing pain thresholds and chronic VNS treatment increasing pain thresholds.
Jeffrey J Borckardt, F Andrew Kozel, Berry Anderson, Angela Walker, Mark S George   +4 more
doaj   +1 more source

LTP-like cortical plasticity predicts conversion to dementia in patients with memory impairment

Brain Stimulation, 2020
Background: New diagnostic criteria consider Alzheimer’s disease (AD) as a clinico-biological entity identifiable in vivo on the presence of specific patterns of CSF biomarkers. Objective: Here we used transcranial magnetic stimulation to investigate the
Francesco Di Lorenzo, Caterina Motta, Elias Paolo Casula, Sonia Bonnì, Martina Assogna, Carlo Caltagirone, Alessandro Martorana, Giacomo Koch   +7 more
doaj   +1 more source

Deep brain and cortical stimulation for epilepsy [PDF]

, 2014
Background : Despite optimal medical treatment, including epilepsy surgery, many epilepsy patients have uncontrolled seizures. In the last decades, interest has grown in invasive intracranial neurostimulation as a treatment for these patients ...
Anderson, Andrade, Becker, Beyenburg, Boon, Borghs, Boëx, Buren, Chabardes, Chkhenkeli, Cramer, Cramer, Curtin, Deeks, Devinsky, Elbourne, Elisevich, Engel, Fisher, Fisher, Fisher, Forsgren, Franzini, Handforth, Hodaie, Jehi, Katariwala, Kellinghaus, Khan, Kwan, Kwan, Kwan, Lim, Lim, McLachlan, Morrell, Neligan, Parrent, Privitera, Raftopoulos, Raftopoulos, Rijckevorsel, Rijckevorsel, Salanova, Schulze-Bonhage, Schulze-Bonhage, Selwa, Stedman, Tellez-Zenteno, Tellez-Zenteno, Tisi, Tomson, Valentin, Velasco, Velasco, Velasco, Velasco, Velasco, Velasco, Vonck, Wiebe, Wille, Wright, Zou   +63 more
core   +1 more source

Inferring Causality from Noninvasive Brain Stimulation in Cognitive Neuroscience

Journal of Cognitive Neuroscience, 2020
Noninvasive brain stimulation (NIBS) techniques, such as transcranial magnetic stimulation or transcranial direct and alternating current stimulation, are advocated as measures to enable causal inference in cognitive neuroscience experiments ...
T. Bergmann, G. Hartwigsen
semanticscholar   +1 more source