Results 51 to 60 of about 639,600 (311)

Neuroplasticity associated with tactile language communication in a deaf-blind subject

Frontiers in Human Neuroscience, 2010
A longstanding debate in cognitive neuroscience pertains to the innate nature of language development and the underlying factors that determine this faculty. We explored the neural correlates associated with language processing in a unique individual who
Souzana Obretenova, Mark A Halko, Ela B Plow, Alvaro Pascual-Leone, Lotfi B Merabet   +4 more
doaj   +1 more source

Electrophysiological signatures predict clinical outcomes after deep brain stimulation of the globus pallidus internus in Meige syndrome [PDF]

, 2021
Objective: Deep brain stimulation (DBS) of the globus pallidus internus (GPi) has been shown to be a safe and effective alternative therapy for ameliorating medically refractory primary Meige syndrome.
Tian, Hong, Zhang, Bo, Zhang, Li, Wang, Liang, Yuan, Yue, Yu, Yanbing, Zhen, Xueke   +6 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

A two-site, open-label, non-randomized trial comparing Focal Electrically-Administered Seizure Therapy (FEAST) and right unilateral ultrabrief pulse electroconvulsive therapy (RUL-UBP ECT)

Brain Stimulation, 2020
Background: Focal Electrically-Administered Seizure Therapy (FEAST) is a form of electroconvulsive therapy (ECT) that spatially focuses the electrical stimulus to initiate seizure activity in right prefrontal cortex.
Gregory L. Sahlem, William V. McCall, E. Baron Short, Peter B. Rosenquist, James B. Fox, Nagy A. Youssef, Andrew J. Manett, Suzanne E. Kerns, Morgan M. Dancy, Laryssa McCloud, Mark S. George, Harold A. Sackeim   +11 more
doaj   +1 more source

Perturbation of resting-state network nodes preferentially propagates to structurally rather than functionally connected regions

Scientific Reports, 2021
Combining Transcranial Magnetic Stimulation (TMS) with electroencephalography (EEG) offers the opportunity to study signal propagation dynamics at high temporal resolution in the human brain.
Davide Momi, Recep A. Ozdemir, Ehsan Tadayon, Pierre Boucher, Alberto Di Domenico, Mirco Fasolo, Mouhsin M. Shafi, Alvaro Pascual-Leone, Emiliano Santarnecchi   +8 more
doaj   +1 more source

Numerical investigation of the electric field distribution induced in the brain by transcranial magnetic stimulation (TMS) [PDF]

, 2004
Introduction.There has been considerable interest over the years in the treatment of serious physiological and clinical conditions, such as depression and pain relief, byutilising electromagnetic fields through Transcranial Magnetic Stimulation (TMS) of ...
Georghiou, G.E., Kim, D., Loukaides, N., Georghiou, G. E., Sykulski, J.K., Kim, Dong-Hun   +5 more
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Deep brain stimulation for treatment resistant obsessive compulsive disorder; an observational study with ten patients under real-life conditions

Frontiers in Psychiatry, 2023
IntroductionObsessive-compulsive disorder (OCD) affects 2–3% of the global population, causing distress in many functioning levels. Standard treatments only lead to a partial recovery, and about 10% of the patients remain treatment-resistant.
Mohamed A. Abdelnaim, Mohamed A. Abdelnaim, Verena Lang-Hambauer, Verena Lang-Hambauer, Tobias Hebel, Stefan Schoisswohl, Stefan Schoisswohl, Martin Schecklmann, Daniel Deuter, Daniel Deuter, Juergen Schlaier, Juergen Schlaier, Berthold Langguth, Berthold Langguth   +13 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Early differences in lassitude predicts outcomes in Stanford Neuromodulation Therapy for difficult to treat depression

npj Mental Health Research
Stanford Neuromodulation Therapy (SNT), has recently shown rapid efficacy in difficult to treat (DTT) depression. We conducted an exploratory analysis of individual symptom improvements during treatment, correlated with fMRI, to investigate this rapid ...
David Benrimoh, Azeezat Azeez, Jean-Marie Batail, Xiaoqian Xiao, Derrick Buchanan, Igor D. Bandeira, Andrew Geoly, Yaakov Keynan, Ian H. Kratter, Nolan R. Williams   +9 more
doaj   +1 more source