Results 61 to 70 of about 2,769,765 (297)

The painfulness of active, but not sham, transcranial magnetic stimulation decreases rapidly over time: Results from the double-blind phase of the OPT-TMS trial

, 2013
Background: Daily left prefrontal repetitive transcranial magnetic stimulation (rTMS) over several weeks is an FDA approved treatment for major depression.
Avery D., Long J.M., McDonald W.M., Durkalski V., Teal J., Pavlicova M., George M.S., Lisanby S.H., Sackeim H.A., Nahas Z.H., Borckardt J.J.   +10 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Current DBS programming

Deep brain stimulation is an established treatment option for various neurological and psychiatric disorders. Throughout its journey as a confirmed long-term efficacious therapeutic option for movement disorders such as Parkinson’ s disease, essential ...
Değirmenci, Yıldız
core   +1 more source

The Influence of Deep Brain Stimulation Intensity and Duration on Symptoms Evolution in an OFF Stimulation Dystonia Study

, 2013
Background: Deep brain stimulation (DBS) of the internal globus pallidus (GPi) is an established therapy for primary generalized dystonia. However, the evolution of dystonia symptoms after DBS discontinuation after years of therapy has only rarely been ...
Ruge, Diane, Limousin, Patricia, Gonzalez, Victoria, Vasques, Xavier, Cif, Laura, Hariz, Marwan I.,, Coubes, Philippe, Rothwell, John   +7 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Brain-state determines learning improvements after transcranial alternating-current stimulation to frontal cortex [PDF]

, 2018
Published in final edited form as: Brain Stimul. 2018 ; 11(4): 723–726. doi:10.1016/j.brs.2018.02.008BACKGROUND Theories of executive control propose that communication between medial frontal cortex (MFC) and lateral prefrontal cortex (lPFC) is ...
Yuqi Deng, Deng, Yuqi, Nguyen, John, John Nguyen, Reinhart, Robert M.G., Robert M.G. Reinhart   +5 more
core   +1 more source

Probabilistic maps for deep brain stimulation – Impact of methodological differences

, 2022
Background: Group analysis of patients with deep brain stimulation (DBS) has the potential to help understand and optimize the treatment of patients with movement disorders.
Österlund, Erik, Österlund, Erik,, Nordin, T, Nordin, Teresa, Hemm, S, Nordin, Teresa,, Hemm-Ode, Simone,, Wårdell, Karin, Fytagoridis, A,, Blomstedt, Patric,, Vogel, Dorian, Hemm-Ode, Simone, Johansson, J, Vogel, Dorian,, Vogel, D, Hemm, Simone,, Osterlund, E, Wårdell, Karin,, Hemm, Simone, Fytagoridis, Anders,, Blomstedt, Patric, Fytagoridis, Anders, Johansson, Johannes,, Wardell, K, Johansson, Johannes, Blomstedt, P   +25 more
core   +1 more source

The effects of direct brain stimulation in humans depend on frequency, amplitude, and white-matter proximity [PDF]

, 2020
BACKGROUND: Researchers have used direct electrical brain stimulation to treat a range of neurological and psychiatric disorders. However, for brain stimulation to be maximally effective, clinicians and researchers should optimize stimulation parameters ...
Jobst, Barbara C, Jacobs, Joshua, Kahana, Michael J., Gross, Robert E, Davis, Kathryn A, Sheth, Sameer A, Zaghloul, Kareem A., Worrell, Gregory A, Jobst, Barbara C., Das, Sandhitsu R., Gorniak, MD, Richard, Gross, Robert E., Zaghloul, Kareem A, Miller, Jonathan F., Gorniak, Richard, Lega, Bradley C, Kahana, Michael J, Watrous, Andrew J, Worrell, Gregory A., Mohan, Uma R, Stein, Joel M, Mohan, Uma R., Miller, Jonathan F, Rizzuto, Daniel S., Sperling, Michael R, Stein, Joel M., Wanda, Paul A., Rizzuto, Daniel S, Sperling, Michael R., Lega, Bradley C., Watrous, Andrew J., Sheth, Sameer A., Wanda, Paul A, Das, Sandhitsu R, Davis, Kathryn A.   +34 more
core   +1 more source

Causal connectivity maps derived from single-pulse interleaved TMS/fMRI

Scientific Reports
Understanding causal interactions between cortical and subcortical brain regions is critical for mapping human functional connectivity. While non-invasive methods such as fMRI and diffusion imaging have provided valuable insights into brain connectivity,
Lison Bossus, Jess Dickson, Camille Blaine, Hasti Khalilkhani, Ahsan Khan, Desmond J. Oathes   +5 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source