Results 71 to 80 of about 639,600 (311)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Using Remotely Supervised At-Home TES for Enhancing Mental Resilience
Frontiers in Human Neuroscience, 2022 We are in the midst of a mental health crisis with major depressive disorder being the most prevalent among mental health disorders and up to 30% of patients not responding to first-line treatments.
Jasmina Paneva +16 more
doaj +1 more source
Caloric vestibular stimulation in aphasic syndrome [PDF]
, 2013 Caloric vestibular stimulation (CVS) is commonly used to diagnose brainstem disorder but its therapeutic application is much less established.
Paul F. Smith +30 more
core +1 more source
A brain network for deep brain stimulation induced cognitive decline in Parkinson's disease [PDF]
, 2022 Reich et al. show that DBS-induced cognitive decline is associated with connectivity between the stimulation site and a specific brain network implicated in lesion-induced memory impairment. Transforming this network into a heat map can help identify DBS
Hsu Joey +10 more
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Modelling the effects of deep brain stimulation in the pedunculopontine tegmental nucleus in Parkinson’s disease [PDF]
, 2014 Based on the belief that it is a locomotor control structure, the pedunculopontine tegmental nucleus (PPTg) has been considered a potential target for deep brain stimulation (DBS) for Parkinson’s disease (PD) patients with symptoms refractory to ...
Gut, Nadine Katrin
core
Transcranial direct current stimulation: State of the art 2008 [PDF]
Effects of weak electrical currents on brain and neuronal function were first described decades ago. Recently, DC polarization of the brain was reintroduced as a noninvasive technique to alter cortical activity in humans. Beyond this, transcranial direct
Paulus, Walter +10 more
core +1 more source
Evidence of transcranial direct current stimulation-generated electric fields at subthalamic level in human brain in vivo [PDF]
, 2018 BACKGROUND:Transcranial direct current stimulation (tDCS) is a promising brain modulation technique for several disease conditions. With this technique, some portion of the current penetrates through the scalp to the cortex and modulates cortical ...
Feng, Wuwei +15 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Brain Stimulation and its Role in Neurological Diseases [PDF]
The growing use of non-invasive brain stimulation in clinical applications reflects its capabilities to transiently modulate cortical excitability, motor and cognitive functions in ways not possible with other techniques. Neurological disorders represent
Zimerman, Maximo +1 more
core +1 more source