Results 31 to 40 of about 574,597 (262)

A pilot randomized controlled trial of supervised, at-home, self-administered transcutaneous auricular vagus nerve stimulation (taVNS) to manage long COVID symptoms

Bioelectronic Medicine, 2022
Background Although the coronavirus disease 19 (COVID-19) pandemic has now impacted the world for over two years, the persistent secondary neuropsychiatric effects are still not fully understood.
Bashar W. Badran, Sarah M. Huffman, Morgan Dancy, Christopher W. Austelle, Marom Bikson, Steven A. Kautz, Mark S. George   +6 more
doaj   +1 more source

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida, Gisela Cristiane Miyamoto, Daniel da Costa Torres, Ian Setubal Reis Chaves, Jonas do Carmo Paschoalin, Braúlio Lima Nascimento, Luciana Dias Chiavegato   +6 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Neuroplasticity associated with tactile language communication in a deaf-blind subject

Frontiers in Human Neuroscience, 2010
A longstanding debate in cognitive neuroscience pertains to the innate nature of language development and the underlying factors that determine this faculty. We explored the neural correlates associated with language processing in a unique individual who
Souzana Obretenova, Mark A Halko, Ela B Plow, Alvaro Pascual-Leone, Lotfi B Merabet   +4 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

A two-site, open-label, non-randomized trial comparing Focal Electrically-Administered Seizure Therapy (FEAST) and right unilateral ultrabrief pulse electroconvulsive therapy (RUL-UBP ECT)

Brain Stimulation, 2020
Background: Focal Electrically-Administered Seizure Therapy (FEAST) is a form of electroconvulsive therapy (ECT) that spatially focuses the electrical stimulus to initiate seizure activity in right prefrontal cortex.
Gregory L. Sahlem, William V. McCall, E. Baron Short, Peter B. Rosenquist, James B. Fox, Nagy A. Youssef, Andrew J. Manett, Suzanne E. Kerns, Morgan M. Dancy, Laryssa McCloud, Mark S. George, Harold A. Sackeim   +11 more
doaj   +1 more source

Perturbation of resting-state network nodes preferentially propagates to structurally rather than functionally connected regions

Scientific Reports, 2021
Combining Transcranial Magnetic Stimulation (TMS) with electroencephalography (EEG) offers the opportunity to study signal propagation dynamics at high temporal resolution in the human brain.
Davide Momi, Recep A. Ozdemir, Ehsan Tadayon, Pierre Boucher, Alberto Di Domenico, Mirco Fasolo, Mouhsin M. Shafi, Alvaro Pascual-Leone, Emiliano Santarnecchi   +8 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Early differences in lassitude predicts outcomes in Stanford Neuromodulation Therapy for difficult to treat depression

npj Mental Health Research
Stanford Neuromodulation Therapy (SNT), has recently shown rapid efficacy in difficult to treat (DTT) depression. We conducted an exploratory analysis of individual symptom improvements during treatment, correlated with fMRI, to investigate this rapid ...
David Benrimoh, Azeezat Azeez, Jean-Marie Batail, Xiaoqian Xiao, Derrick Buchanan, Igor D. Bandeira, Andrew Geoly, Yaakov Keynan, Ian H. Kratter, Nolan R. Williams   +9 more
doaj   +1 more source

Deep brain stimulation for treatment resistant obsessive compulsive disorder; an observational study with ten patients under real-life conditions

Frontiers in Psychiatry, 2023
IntroductionObsessive-compulsive disorder (OCD) affects 2–3% of the global population, causing distress in many functioning levels. Standard treatments only lead to a partial recovery, and about 10% of the patients remain treatment-resistant.
Mohamed A. Abdelnaim, Mohamed A. Abdelnaim, Verena Lang-Hambauer, Verena Lang-Hambauer, Tobias Hebel, Stefan Schoisswohl, Stefan Schoisswohl, Martin Schecklmann, Daniel Deuter, Daniel Deuter, Juergen Schlaier, Juergen Schlaier, Berthold Langguth, Berthold Langguth   +13 more
doaj   +1 more source