Results 111 to 120 of about 4,226 (251)

Toward Enhanced Safety Management in Wave Energy Power Plant Construction Projects: FMEA and HAZOP Combination

open access: yesSafety Science and Technology, EarlyView.
Consolidated FMEA–HAZOP safety management framework for WEC construction projects. ABSTRACT This study presents an advanced safety management framework for “Wave Energy Converter” (WEC) projects, addressing the inherent uncertainty, technological complexity, and environmental exposure of offshore renewable energy systems.
Panagiotis K. Marhavilas   +4 more
wiley   +1 more source

Four‐dimensional immuno‐mechanobiomaterials: Dynamic material cues that program host response to prevent fibrosis and enable regeneration

open access: yesVIEW, EarlyView.
Dynamic immuno‐mechanobiomaterials with time‐programmed mechanical adaptation orchestrate host responses through precise mechanotransduction and immune‐stromal regulation. These adaptive biomaterials minimize mechanical mismatch, attenuate the forign dy response and fibrosis, promote angiogenesis and controlled extracellular matrix remodeling, and ...
Gobinath Vellapalayam Manoharan   +4 more
wiley   +1 more source

Protodesnitazene: The identification and tissue distribution of a new nitazene

open access: yesJournal of Forensic Sciences, EarlyView.
Abstract Multiple new analogues from the 2‐benzyl benzimidazole or “nitazene” class of drugs have emerged on the drug market in recent years. Nitazenes are highly potent μ‐opioid receptor agonists that present a substantial public health concern due to their elevated risk of severe toxicity in overdose and their significant potential for misuse.
Andrew Griffiths   +4 more
wiley   +1 more source

Impact of barometric pressure on blood pressure during dialysis: Introducing intradialytic time‐averaged cumulative systolic blood pressure (TACsBP‐inD) as a new metric

open access: yesTherapeutic Apheresis and Dialysis, Volume 29, Issue 3, Page 525-534, June 2025.
Abstract Background Blood pressure is a crucial risk factor for hemodialysis patients, but the specific impact of weather factors, particularly barometric pressure, on blood pressure remains unclear. This study aims to examine the relationship between barometric pressure and blood pressure in hemodialysis patients. Methods We conducted a single‐center,
Kosaku Iwatsubo   +2 more
wiley   +1 more source

Parallel Liquid Biopsy Analysis of miR‐371a‐3p and Cell‐Free DNA in an Unselected Cohort of Patients With Testicular Germ Cell Tumors

open access: yesAndrology, EarlyView.
ABSTRACT Background Despite robust data showing strong potential to improve diagnosis and disease monitoring in testicular germ cell tumors (TGCTs), miR‐371a‐3p testing has not yet been implemented in routine clinical practice. Cell‐free DNA (cfDNA) represents another promising liquid biopsy biomarker that may provide complementary molecular ...
Laura Matouskova   +6 more
wiley   +1 more source

Adenosine—A Regulator of Human Testicular Peritubular Cells

open access: yesAndrology, EarlyView.
ABSTRACT Background Extracellular purines, in particular ATP and adenosine, are regulators of physiological and pathophysiological processes throughout the human body. Roles in the human testis are emerging and include actions on peritubular cells, which form the wall of seminiferous tubules.
Lina Scholz   +12 more
wiley   +1 more source

Impact of incretin analogues on lipid and lipoprotein metabolism in obesity and diabetes

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Incretin‐based therapies have gained momentum as a key strategy for reducing cardiovascular risk in individuals with obesity and/or type 2 diabetes (T2D). It remains unclear whether the cardiovascular benefits reflect a direct reduction in atherogenic lipoproteins—namely, low‐density lipoproteins (LDL), very low‐density lipoproteins (VLDL) and
Andrea Baragetti, Giuseppe Danilo Norata
wiley   +1 more source

TRPM3 regulates fear memory encoding and seizure susceptibility in the lateral amygdala

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and purpose TRPM3 is best known for its role as a peripheral sensor of pain and heat. Recent studies reporting gain‐of‐function TRPM3 mutations in patients with neurodevelopmental and epilepsy‐associated disorders suggest a previously unrecognized role of this channel in the brain.
Attila Gyéresi   +12 more
wiley   +1 more source

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