Results 81 to 90 of about 831,573 (301)

Early prediction of neurological outcome after barbiturate coma therapy in patients undergoing brain tumor surgery

PLoS ONE, 2019
After a difficult brain tumor surgery, refractory intracranial hypertension (RICH) may occur due to residual tumor or post-operative complications such as hemorrhage, infarction, and aggravated brain edema. We investigated which predictors are associated
J. Ryu, Wonkyung Jung, Y. Jung, D. Kwon, K. Kang, Hyeok Choi, D. Kong, H. Seol, Jung-Il Lee   +8 more
semanticscholar   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Role of Diffusion Tensor Imaging in Brain Tumor Surgery

Asian Journal of Neurosurgery, 2018
Object: The objective is to evaluate the role of diffusion tensor imaging (DTI) in intra-axial brain tumor cases (gliomas and metastasis). To preoperatively assess the integrity and location of white matter (WM) tracts and plan the surgical corridor to ...
Amitesh Dubey, R. Kataria, V. Sinha
semanticscholar   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou, Marc Jaskir, Julian Gal, Yombe Fonkeu, Christos Davatzikos, MacLean P. Nasrallah, Jose Garcia, Rubo Xing, Stephen J. Bagley, Arati Desai, Richard E. Phillips, Steven Tobochnik, Colin A. Ellis, James J. Gugger, Nishant Sinha, Joel M. Stein, Kathryn A. Davis   +16 more
wiley   +1 more source

Molecular Targeted NIR-II Probe for Image-Guided Brain Tumor Surgery

Bioconjugate chemistry, 2018
Optical imaging strategies for improving delineation of glioblastoma (GBM) is highly desired for guiding surgeons to distinguish cancerous tissue from healthy and precious brain tissue.
Sorel Kurbegovic, K. Juhl, Hao Chen, Chunrong Qu, Bingbing Ding, J. Leth, K. Drzewiecki, A. Kjaer, Zhen Cheng   +8 more
semanticscholar   +1 more source

[AWAKE SURGERY FOR A PRIMARY BRAIN TUMOR].

Lijecnicki vjesnik, 2015
Awake brain surgery has been approved as a safe and efficaceous operative procedure with the goal of maximal tumor resection and preservation of neurological function. This case report presents the first full awake primary brain tumor surgical procedure performed in Croatia.
Rotim, K, Sajko, T, Batinica IM, Schoenwald MZ, Benko, M, Kovačević, M.   +5 more
openaire   +2 more sources

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig, Nadav Amir, Maya Schiller, Roni Loebenstein, Johnatan Nissan, Marina Boxer, Shany Guly Gofrit, Gal Goshen, Sándor Beniczky, Nicola Maggio   +9 more
wiley   +1 more source

The CXCL16-CXCR6 axis in glioblastoma modulates T-cell activity in a spatiotemporal context

Frontiers in Immunology
IntroductionGlioblastoma multiforme (GBM) pathobiology is characterized by its significant induction of immunosuppression within the tumor microenvironment, predominantly mediated by immunosuppressive tumor-associated myeloid cells (TAMCs). Myeloid cells
Tzu-Yi Chia, Tzu-Yi Chia, Leah K. Billingham, Leah K. Billingham, Lauren Boland, Lauren Boland, Lauren Boland, Joshua L. Katz, Joshua L. Katz, Victor A. Arrieta, Victor A. Arrieta, Jack Shireman, Aurora-Lopez Rosas, Aurora-Lopez Rosas, Susan L. DeLay, Susan L. DeLay, Kaylee Zillinger, Kaylee Zillinger, Yuheng Geng, Yuheng Geng, Jeandre Kruger, Jeandre Kruger, Caylee Silvers, Caylee Silvers, Hanxiang Wang, Hanxiang Wang, Gustavo Ignacio Vazquez Cervantes, Gustavo Ignacio Vazquez Cervantes, David Hou, David Hou, Si Wang, Si Wang, Hanxiao Wan, Hanxiao Wan, Adam Sonabend, Adam Sonabend, Peng Zhang, Peng Zhang, Catalina Lee-Chang, Catalina Lee-Chang, Jason Miska, Jason Miska   +41 more
doaj   +1 more source