Results 11 to 20 of about 6,149,012 (253)

Novel insight into histological and molecular astrocytoma, IDH‐mutant, Grade 4 by the updated WHO classification of central nervous system tumors

Cancer Medicine, 2023
Background The latest fifth edition of the World Health Organization (WHO) classification of the central nervous system (CNS) tumors (WHO CNS 5 classification) released in 2021 defined astrocytoma, IDH‐mutant, Grade 4.
Wenlin Chen, Siying Guo, Yaning Wang, Yixin Shi, Xiaopeng Guo, Delin Liu, Yilin Li, Yuekun Wang, Hao Xing, Yu Xia, Junlin Li, Jiaming Wu, Tingyu Liang, Hai Wang, Qianshu Liu, Shanmu Jin, Tian Qu, Huanzhang Li, Tianrui Yang, Kun Zhang, Yu Wang, Wenbin Ma   +21 more
doaj   +1 more source

Blood–Brain Barrier in Brain Tumors: Biology and Clinical Relevance

International Journal of Molecular Sciences, 2021
The presence of barriers, such as the blood–brain barrier (BBB) and brain–tumor barrier (BTB), limits the penetration of antineoplastic drugs into the brain, resulting in poor response to treatments.
F. Mo, A. Pellerino, R. Soffietti, R. Rudà   +3 more
semanticscholar   +1 more source

The CDK inhibitor AT7519 inhibits human glioblastoma cell growth by inducing apoptosis, pyroptosis and cell cycle arrest

Cell Death and Disease, 2023
Glioblastoma multiforme (GBM) is the most lethal primary brain tumor with a poor median survival of less than 15 months. However, clinical strategies and effective therapies are limited.
Wenpeng Zhao, Liang Zhang, Yaya Zhang, Zhengye Jiang, Hanwen Lu, Yuanyuan Xie, Wanhong Han, Wentao Zhao, Jiawei He, Zhongjie Shi, Huiying Yang, Junjie Chen, Sifang Chen, Zhangyu Li, Jianyao Mao, Liwei Zhou, Xin Gao, Wenhua Li, Guowei Tan, Bingchang Zhang, Zhanxiang Wang   +20 more
doaj   +1 more source

A Novel Deep Learning Method for Recognition and Classification of Brain Tumors from MRI Images

Diagnostics, 2021
A brain tumor is an abnormal growth in brain cells that causes damage to various blood vessels and nerves in the human body. An earlier and accurate diagnosis of the brain tumor is of foremost important to avoid future complications. Precise segmentation
Momina Masood, Tahira Nazir, Marriam Nawaz, Awais Mehmood, Junaid Rashid, Hyuk-Yoon Kwon, Toqeer Mahmood, A. Hussain   +7 more
semanticscholar   +1 more source

The 2021 WHO Classification of Tumors of the Central Nervous System: a summary.

Neuro-Oncology, 2021
The fifth edition of the WHO Classification of Tumors of the Central Nervous System (CNS), published in 2021, is the sixth version of the international standard for the classification of brain and spinal cord tumors.
D. Louis, A. Perry, P. Wesseling, D. Brat, I. Cree, D. Figarella-Branger, C. Hawkins, H. Ng, S. Pfister, G. Reifenberger, R. Soffietti, A. von Deimling, D. Ellison   +12 more
semanticscholar   +1 more source

Prognostic Value of Choline and Other Metabolites Measured Using ¹H-Magnetic Resonance Spectroscopy in Gliomas: A Meta-Analysis and Systemic Review

Metabolites, 2022
Glioma is the most prevalent primary central nervous system malignant tumor, with high heterogeneity observed among different grades; therefore, non-invasive prediction of prognosis could improve the clinical management of patients with glioma.
Yixin Shi, Delin Liu, Ziren Kong, Qianshu Liu, Hao Xing, Yuekun Wang, Yu Wang, Wenbin Ma   +7 more
doaj   +1 more source

Classification of Brain Tumors from MRI Images Using a Convolutional Neural Network

Applied Sciences, 2020
The classification of brain tumors is performed by biopsy, which is not usually conducted before definitive brain surgery. The improvement of technology and machine learning can help radiologists in tumor diagnostics without invasive measures.
Milica M. Badža, M. Barjaktarović
semanticscholar   +1 more source

An online survival predictor in glioma patients using machine learning based on WHO CNS5 data

Frontiers in Neurology, 2023
BackgroundThe World Health Organization (WHO) CNS5 classification system highlights the significance of molecular biomarkers in providing meaningful prognostic and therapeutic information for gliomas.
Liguo Ye, Lingui Gu, Zhiyao Zheng, Zhiyao Zheng, Zhiyao Zheng, Xin Zhang, Hao Xing, Xiaopeng Guo, Xiaopeng Guo, Wenlin Chen, Yaning Wang, Yuekun Wang, Tingyu Liang, Hai Wang, Yilin Li, Yilin Li, Shanmu Jin, Shanmu Jin, Yixin Shi, Yixin Shi, Delin Liu, Delin Liu, Tianrui Yang, Tianrui Yang, Qianshu Liu, Qianshu Liu, Congcong Deng, Yu Wang, Yu Wang, Wenbin Ma, Wenbin Ma   +30 more
doaj   +1 more source

Revisiting the Immunological Aspects of Temozolomide Considering the Genetic Landscape and the Immune Microenvironment Composition of Glioblastoma

Frontiers in Oncology, 2021
The microenvironment (ME) plays a critical role in causing glioblastoma (GBM) to be a moving and incurable target. The main features governing the interaction between cancer cells and the ME include dependency, promotion, and in rare cases, even ...
Natalia Di Ianni, Natalia Di Ianni, Martina Maffezzini, Martina Maffezzini, Marica Eoli, Serena Pellegatta, Serena Pellegatta   +6 more
doaj   +1 more source

Brain tumors induced in rats by human adenovirus type 12 [PDF]

, 1974
Oncogenesis of human adenovirus type 12 in the brain of rats was examined. Newborn rats of Sprague-Dawley and Donryu　strains were injected intracranially with human adenovirus type 12.　The incidence of intracranial tumors was 91% (30/33) in
Matsuo, Keisuke, Murao, Tsuyoshi, Ogawa, Katsuo, Ohmori, Hiroyuki, Sonobe, Hiroshi, Tsutsumi, Akira   +5 more
core   +1 more source