Results 71 to 80 of about 307,291 (261)

Rational Design of Inner Ear Drug Delivery Systems

open access: yesAdvanced Science, EarlyView.
Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu   +5 more
wiley   +1 more source

Synaptic Inhibition Influences the Temporal Coding Properties of Medial Superior Olivary Neurons. An in vitro Study [PDF]

open access: yes, 1994
The medial superior olive (MSO) functions as a coincidence detector for interaural time and phase differences by integrating excitatory synaptic inputs.
Grothe, Benedikt, Sanes, Dan H.
core   +1 more source

Small Extracellular Vesicles Orchestrate Cisplatin‐Induced Ototoxicity: Potential Biomarker and Targets Discovery

open access: yesAdvanced Science, EarlyView.
Cisplatin causes reactive oxygen species accumulation, leading to apoptosis and inflammation in cochlear hair cells. Small extracellular vesicles primarily derived from the damaged hair cells likely contribute to cisplatin‐induced ototoxicity, carrying a variety of microRNAs and proteins.
Jingru Ai   +14 more
wiley   +1 more source

Head-related Impulse Response Cues for Spatial Auditory Brain-computer Interface [PDF]

open access: yes, 2015
This study provides a comprehensive test of a head-related impulse response (HRIR) cues for a spatial auditory brain-computer interface (saBCI) speller paradigm. We present a comparison with the conventional virtual sound headphone-based spatial auditory modality. We propose and optimize the three types of sound spatialization settings using a variable
arxiv   +1 more source

Neurologic Deficits Including Auditory Loss and Recovery of Function in Horses with Temporohyoid Osteoarthropathy. [PDF]

open access: yes, 2015
BackgroundAuditory loss is a common deficit in horses with temporohyoid osteoarthropathy (THO), however, recovery of function is unknown.Hypothesis/objectivesTo investigate neurologic function with emphasis in audition in horses with THO after treatment.
Aleman, M   +3 more
core   +2 more sources

Assessment of auditory dysfunction as an extra-articular manifestation in rheumatoid arthritis using brainstem auditory-evoked potential

open access: yesJournal of Medicine in Scientific Research, 2021
Objectives The paper aims to study brainstem auditory-evoked potential parameter changes in rheumatoid arthritis (RA) patients, and their relation to the duration of illness, degree of disease activity, functional stage of the disease, and intensity of ...
Abeer H Ismaiel   +3 more
doaj   +1 more source

Visualization of the Spiral Ganglion Neuron in Vivo Using a Novel 177Lu Nuclear Molecule Label

open access: yesAdvanced Science, EarlyView.
The study developed and validated a radionuclide‐labeled anti‐VGLUT1 antibody probe for the first nuclear imaging of cochlear spiral ganglion neurons (SGNs) in vivo. This approach may provide aid in screening candidates suitable for CI surgery by quantifying the number of surviving SGNs, and predicting the potential for postoperative hearing ...
Chenyang Kong   +11 more
wiley   +1 more source

Applicability of subcortical EEG metrics of synaptopathy to older listeners with impaired audiograms [PDF]

open access: yes, 2019
Emerging evidence suggests that cochlear synaptopathy is a common feature of sensorineural hearing loss, but it is not known to what extent electrophysiological metrics targeting synaptopathy in animals can be applied to people, such as those with ...
Garrett, Markus, Verhulst, Sarah
core   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

open access: yesEpilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Towards auditory attention decoding with noise-tagging: A pilot study [PDF]

open access: yes9th Graz Brain-Computer Interface Conference (2024) 337-342
Auditory attention decoding (AAD) aims to extract from brain activity the attended speaker amidst candidate speakers, offering promising applications for neuro-steered hearing devices and brain-computer interfacing. This pilot study makes a first step towards AAD using the noise-tagging stimulus protocol, which evokes reliable code-modulated evoked ...
arxiv   +1 more source

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