Results 11 to 20 of about 77 (53)

Sleep magnetoencephalography enhances detection and source imaging of seizures and fast oscillations in focal cortical dysplasia

open access: yesEpilepsia, EarlyView.
Abstract Objective Focal cortical dysplasia (FCD) causes drug‐resistant epilepsy requiring presurgical evaluation. Invasive electroencephalographic (EEG) studies demonstrate that sleep modulates epileptic activity, including interictal epileptiform discharges (IEDs), fast oscillations (FOs) in the beta (14–40 Hz) and gamma (40–80 Hz) frequency bands ...
Marcel Heers   +13 more
wiley   +1 more source

Spatiotemporal Encoding With Nonlinear Gradient Hardware Using Pulseq: From Principles to Practical Demonstration

open access: yesMagnetic Resonance in Medicine, Volume 95, Issue 6, Page 3187-3198, June 2026.
Purpose Provide the theoretical foundation and the first practical demonstration of spatiotemporal encoding (SPEN) using additional nonlinear gradient hardware. Methods The quadratic phase profile can be generated either by a chirped‐RF pulse combined with a constant gradient or, directly, by a quadratic gradient pulse.
Andreas Holl   +8 more
wiley   +1 more source

Sleep enhances gamma oscillations in the seizure onset zone and broadband activity in the irritative zone of focal cortical dysplasia

open access: yesEpilepsia Open, Volume 11, Issue 2, Page 435-451, April 2026.
Abstract Objective Focal cortical dysplasia (FCD) is a leading cause of drug‐resistant epilepsy and is associated with sleep‐related seizures, yet the underlying electrophysiological mechanisms during different brain states remain poorly understood. We investigated whether fast oscillations (FOs) within the seizure onset zone (SOZ) and irritative zone (
Mohammad F. Khazali   +14 more
wiley   +1 more source

Metal Brazing‐Free Ceramic‐to‐Ceramic Hermetic Sealing for All‐Ceramic Active Implantable Devices

open access: yesJournal of the American Ceramic Society, Volume 109, Issue 4, April 2026.
ABSTRACT Hermetic sealing of engineering ceramic‐based active implantable medical devices (AIMDs) is a crucial part of their fabrication and significantly influences the reliability and lifetime of the devices once implanted within a biological environment.
Shaikh Nayeem Faisal   +6 more
wiley   +1 more source

Establishment of High Channel‐Count Packaging in Active Implantable Medical Devices for Neuroprosthesis

open access: yesJournal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 114, Issue 3, March 2026.
ABSTRACT Neuroprostheses have contributed extensively to humankind's capacity to treat disease and injury. Hearing loss is routinely overcome; pain is controlled; and myriad neurological, sensory, motor, and psychological disorders are managed through interventions involving neuromodulation.
Gregg Suaning   +7 more
wiley   +1 more source

Differences and Commonalities of Electrical Stimulation Paradigms After Central Paralysis and Amputation

open access: yesArtificial Organs, Volume 49, Issue 12, Page 1723-1732, December 2025.
Invasive and non‐invasive functional electrical stimulation (FES) is a well‐established method to partially restore function after paralysis and deliver sensory feedback after amputation. This work summarizes the current state‐of‐the‐art of FES for restoring function, supporting rehabilitation therapy, and assistive devices.
Thomas Stieglitz   +3 more
wiley   +1 more source

Challenges and Opportunities in Combining Ultrasound and Inductive Coupling for Energy Supply and Bidirectional Data Exchange in Bioelectronics Medicine Implant Networks

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 11, November 2025.
In this contribution, it is shown that miniaturized nerve stimulation implants can be used in collaborative networks. Inductive links and ultrasound are combined to supply these implants with energy and data; the advantages and disadvantages of each method, as well as safety risks and possibilities for improvement are discussed and the best ...
Benedikt Szabo   +5 more
wiley   +1 more source

The impact of EEG preprocessing parameters on ultra‐low‐power seizure detection

open access: yesEpilepsia, Volume 66, Issue 10, Page 3895-3906, October 2025.
Abstract Objective Closed‐loop neurostimulation is a promising treatment for drug‐resistant focal epilepsy. A major challenge is fast and reliable seizure detection via electroencephalography (EEG). Although many approaches have been published, they often lack statistical power and practical utility.
Patrick Reisinger   +8 more
wiley   +1 more source

Fabrication of a Stable, Low‐Cost, Patient‐Specific, Brain Phantom with Ventricles for Ultrasound Imaging

open access: yesAdvanced Engineering Materials, Volume 27, Issue 18, September 2025.
Patient‐specific brain phantoms can replace animal trials, aid presurgical training, and enable in silico disease research on cerebrospinal fluid and ventricles. This study presents a method to create ventricular brain phantoms from three‐dimensional magnetic resonance images brain scans, resulting in durable, tunable, reproducible models that mimic ...
Kajal Chandraprakash Jain   +3 more
wiley   +1 more source

Covalent Binding of Dexamethasone to Polyimide Improves Biocompatibility of Neural Implantable Devices

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 21, August 19, 2025.
The covalent binding of dexamethasone to the surface of polyimide represents the electrically inert part of implantable intraneural devices. This ensures a sustained release of the drug for 9 weeks. In vitro and in vivo tests confirm the reduction of the foreign body reactions and the improved biocompatibility of dexamethasone functionalized polyimide.
Giulia Turrin   +19 more
wiley   +1 more source

Home - About - Disclaimer - Privacy