Results 11 to 20 of about 62 (45)
Epilepsia Open, EarlyView.Abstract Objective Focal cortical dysplasia (FCD) is a leading cause of drug‐resistant epilepsy and is associated with sleep‐related seizures, yet the underlying electrophysiological mechanisms during different brain states remain poorly understood. We investigated whether fast oscillations (FOs) within the seizure onset zone (SOZ) and irritative zone (
Mohammad F. Khazali +14 more
wiley +1 more source
Magnetic Resonance in Medicine, EarlyView.Purpose Provide the theoretical foundation and the first practical demonstration of spatiotemporal encoding (SPEN) using additional nonlinear gradient hardware. Methods The quadratic phase profile can be generated either by a chirped‐RF pulse combined with a constant gradient or, directly, by a quadratic gradient pulse.
Andreas Holl +8 more
wiley +1 more source
Artificial Organs, Volume 49, Issue 12, Page 1723-1732, December 2025.Invasive and non‐invasive functional electrical stimulation (FES) is a well‐established method to partially restore function after paralysis and deliver sensory feedback after amputation. This work summarizes the current state‐of‐the‐art of FES for restoring function, supporting rehabilitation therapy, and assistive devices.
Thomas Stieglitz +3 more
wiley +1 more source
Advanced Intelligent Systems, Volume 7, Issue 11, November 2025.In this contribution, it is shown that miniaturized nerve stimulation implants can be used in collaborative networks. Inductive links and ultrasound are combined to supply these implants with energy and data; the advantages and disadvantages of each method, as well as safety risks and possibilities for improvement are discussed and the best ...
Benedikt Szabo +5 more
wiley +1 more source
The impact of EEG preprocessing parameters on ultra‐low‐power seizure detection
Epilepsia, Volume 66, Issue 10, Page 3895-3906, October 2025.Abstract Objective Closed‐loop neurostimulation is a promising treatment for drug‐resistant focal epilepsy. A major challenge is fast and reliable seizure detection via electroencephalography (EEG). Although many approaches have been published, they often lack statistical power and practical utility.
Patrick Reisinger +8 more
wiley +1 more source
Advanced Engineering Materials, Volume 27, Issue 18, September 2025.Patient‐specific brain phantoms can replace animal trials, aid presurgical training, and enable in silico disease research on cerebrospinal fluid and ventricles. This study presents a method to create ventricular brain phantoms from three‐dimensional magnetic resonance images brain scans, resulting in durable, tunable, reproducible models that mimic ...
Kajal Chandraprakash Jain +3 more
wiley +1 more source
Advanced Healthcare Materials, Volume 14, Issue 21, August 19, 2025.The covalent binding of dexamethasone to the surface of polyimide represents the electrically inert part of implantable intraneural devices. This ensures a sustained release of the drug for 9 weeks. In vitro and in vivo tests confirm the reduction of the foreign body reactions and the improved biocompatibility of dexamethasone functionalized polyimide.
Giulia Turrin +19 more
wiley +1 more source
Advanced Materials Interfaces, Volume 12, Issue 9, May 5, 2025.Brain movement significantly impacts the biocompatibility of neural probes due to continuous strain on neural tissue. This study examines strain profiles across various brain models and movement types, challenging the 5% damage threshold at the electrode–tissue interface.
Ali Sharbatian +3 more
wiley +1 more source
Advanced Materials Interfaces, Volume 12, Issue 9, May 5, 2025.Neural Device Development In article 2401001, Danesh Ashouri Vajari, Thomas Stieglitz, and co‐workers investigate the impact of brain movement on the biocompatibility of neural probes by simulating strain profiles at the electrode‐tissue interface under various displacements.
Ali Sharbatian +3 more
wiley +1 more source
Dysregulation of Myelination in Focal Cortical Dysplasia Type II of the Human Frontal Lobe
Glia, Volume 73, Issue 5, Page 928-947, May 2025.Main Points FCD IIa shows a normal radial myelin fiber pattern, thinner myelin sheaths and reduced myelin synthesis. FCD IIb has disorganized myelinated fibers, thicker myelin sheaths, more oligodendrocytes, and an increased transcription rate of myelin genes.
Catharina Donkels +14 more
wiley +1 more source