Results 41 to 50 of about 29,519 (246)

Data‐Driven Bulldozer Blade Control for Autonomous Terrain Leveling

open access: yesAdvanced Robotics Research, EarlyView.
A simulation‐driven framework for autonomous bulldozer leveling is presented, combining high‐fidelity terramechanics simulation with a neural‐network‐based reduced‐order model. Gradient‐based optimization enables efficient, low‐level blade control that balances leveling quality and operation time.
Harry Zhang   +5 more
wiley   +1 more source

New Active Cooling System to Prevent an Overheating on the Vehicle Disc Brake

open access: yesJIRAE (International Journal of Industrial Research and Applied Engineering), 2018
The brake is a major and vital component to slow down and stop a vehicle. If the brake malfunctions, it can cause a fatal accident or seriously injure either passenger or other road users.
Joni Dewanto   +2 more
doaj   +1 more source

Platelet Rubicon Bidirectional Regulation of GPVI and Integrin αIIbβ3 Signaling Mitigates Stroke Infarction Without Compromising Hemostasis

open access: yesAdvanced Science, EarlyView.
This study identifies Rubicon as a key platelet protein that bidirectionally regulates GPVI and integrin αIIbβ3 signaling. Platelet Rubicon protects against cerebral ischemia‐reperfusion injury by limiting infarction without increasing hemorrhage.
Xiaoyan Chen   +11 more
wiley   +1 more source

Stability Study of Friction Vibration for Urban Rail Transit Train Disc Braking System Based on LuGre Model

open access: yesChengshi guidao jiaotong yanjiu
[Objective] The complexity and variability of friction in urban rail transit train disc brakes make it challenging for traditional static friction models to reveal the dynamic characteristics of the braking system.
FANG Hao   +5 more
doaj   +1 more source

A trailer car dynamics model considering brake rigging of a high-speed train and its application

open access: yesRailway Engineering Science, 2023
Brake systems are essential for the speed regulation or braking of a high-speed train. The vehicle dynamic performance under braking condition is complex and directly affects the reliability and running safety.
Zhiwei Wang   +4 more
doaj   +1 more source

The Disordered Region of ASXL1 Acts as an Auto‐Regulator Through Condensation

open access: yesAdvanced Science, EarlyView.
ASXL1's long IDR encodes an electrostatic “basic platform + acidic brake” that autoregulates condensation. Truncation at a clinical hotspot lifts this brake, forming condensates that retarget BRD2, remodel local chromatin accessibility, and impair neutrophil maturation.
Xiao Fang, Qiwei Li, Wenqing Zhang
wiley   +1 more source

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

open access: yesAdvanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li   +8 more
wiley   +1 more source

Loss of SOCS1 in Donor T Cells Exacerbates Intestinal GVHD by Driving a Chemokine‐Dependent Pro‐Inflammatory Immune Microenvironment

open access: yesAdvanced Science, EarlyView.
T cell‐specific Socs1 knockout leads to inflammatory differentiation of CD8+ T cells, prompting the STAT1/2 complex to drive the activation of Ccl5, Ccr5, and Cxcr3, and promoting the skewing of monocytes toward a pro‐inflammatory M1 macrophage lineage.
Zhigui Wu   +14 more
wiley   +1 more source

In Situ X‐Ray Tomography and Acoustic Emission Monitoring of Damage Evolution in C/C‐SiC Composites Fabricated by Liquid Silicon Infiltration

open access: yesAdvanced Science, EarlyView.
This study investigates how the internal structure of fiber‐reinforced ceramic composites affects their resistance to damage. By combining 3D X‐ray imaging with acoustic emission monitoring during mechanical testing, it reveals how silicon distribution influences crack formation.
Yang Chen   +7 more
wiley   +1 more source

Reactive Braking System

open access: yesInternational Journal of Engineering & Technology, 2018
This paper is based on the simplifying technique of the existing technology called Autonomous Emergency Braking (AEB) by using a simple electronic setup which can be easily installed in all the existing four-wheelers without changing its existing working system.
Nagendran N   +5 more
openaire   +2 more sources

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