Results 231 to 240 of about 159,311 (302)

Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt

British Journal of Pharmacology, EarlyView.
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown, Alan Armstrong, David J. Mann   +2 more
wiley   +1 more source

Real-Time Defect Identification in Automotive Brake Calipers Using PCA-Optimized Feature Extraction and Machine Learning. [PDF]

Sensors (Basel)
Lee J, Woo U, Lee MH, Kim JY, Choi H, Oh T.   +5 more
europepmc   +1 more source

Comprehensive transduceromic profiling of NOP receptor ligands at different Gα subunits

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose The nociceptin/orphanin FQ (N/OFQ) peptide receptor (NOP) is an opioid receptor family member with distinct pharmacology and broad therapeutic potential. NOP receptors regulate functions such as nociception, stress reactivity, reward, mood, autonomic tone, immunity and sleep/wake cycle.
Davide Malfacini, Riccardo Camilotto, Michele Maritan, Erika Morrone, Stephen Afriyie Boateng, Anna Vacilotto, Salvatore Pacifico, Remo Guerrini, Nurulain T. Zaveri, Girolamo Calo'   +9 more
wiley   +1 more source

Experimental investigation of Al₂O₃ and CeO₂ nanoparticle additives in diesel-cottonseed biodiesel (CSOME) blends for performance and emission mitigation in a CI engine. [PDF]

Sci Rep
Dessie D, Yeshanew ES, Nallamothu RB, Gashaw G.   +3 more
europepmc   +1 more source

Parent's Perceptions of the Family Impacts of COVID‐19 Lockdowns on Themselves and Siblings of Children With Developmental Disabilities: ‘No Time to Breathe’

Child &Family Social Work, EarlyView.
ABSTRACT Family members may be impacted by complex care requirements around childhood disability, although little research provides guidance on the changing needs of families under unexpected circumstances. This study investigated parents' experiences and reports of the impact of COVID‐19 lockdowns in Australia on family members in families raising a ...
Helen Bourke‐Taylor, Monica Leo, Loredana Tirlea, Ayla Baydan, Ted Brown, Luke Robinson, Tim Moore   +6 more
wiley   +1 more source

A Comparative Performance Analysis of Load Cell and Hall-Effect Brake Sensors in Sim Racing. [PDF]

Sensors (Basel)
Joyce JM, Toth AJ, Campbell MJ.
europepmc   +1 more source

INBOARD BRAKING SYSTEM

International Research Journal of Modernization in Engineering Technology and Science
openaire   +1 more source

Experimental investigation on impact of fuel jet size on performance of gasoline-ethanol blend in a SI engine vehicle. [PDF]

Sci Rep
Tafesse D, Nallamothu RB.
europepmc   +1 more source

Performance and emission optimization of a CRDI engine in RCCI mode using hydrogen enriched biodiesel through grey relational analysis approach. [PDF]

PLoS One
Shinil Kumar AD, Hebballi VV, Panda JK.
europepmc   +1 more source

Performance and emission characteristics of waste cooking oil biodiesel blends in sustainable fuel applications. [PDF]

Sci Rep
Azarudeen JM, Anish M, Babu LG, Sivaram AR, Punitha N, Muniyappan K, Giri J, Kanan M, Jayaraman J, Baskar S.   +9 more
europepmc   +1 more source