Results 191 to 200 of about 7,448 (261)

Comparison of Performance Criteria of Vehicle Brake Pad Biopolymers Derived from Renewable Biomass. [PDF]

Polymers (Basel)
Yavuz H.
europepmc   +1 more source

Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt

British Journal of Pharmacology, EarlyView.
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown, Alan Armstrong, David J. Mann   +2 more
wiley   +1 more source

Effects of High-Velocity Elbow Manipulation on Forearm Muscle Electromyographic Recovery in Karting Drivers: A Randomized Within-Participant Sham-Controlled Trial. [PDF]

J Clin Med
Studnicki R, Zarembski A, Wasilewska J, Trąbka B.   +3 more
europepmc   +1 more source

Targeting Cell Cycle Vulnerabilities in Cancers: Emerging Strategies for Therapeutic Development

Cancer Science, EarlyView.
Dysregulated cell cycle control often involves alternative compensatory pathways in cancers to maintain its robustness but provide unique targetable vulnerabilities. We overview recent insights on cancer‐specific vulnerabilities across the cell cycle and discuss how these can be used to develop new therapeutic strategies.
Nana Kamakura, Minji Jo, Motoko Takahashi, Toru Hirota   +3 more
wiley   +1 more source

Synergistically Reinforced Copper-Free Friction Materials with Agricultural Wastes and Carbon Fibers: Evaluation of Tribological Performance. [PDF]

Materials (Basel)
Tian Y, Huang K, Xu Z, Zhuansun Y, Ma Y.
europepmc   +1 more source

tRNA‐Derived Small RNAs in Digestive Cancers: From Translational Regulation to Immune and Extracellular Communication

Cancer Science, EarlyView.
tRNA‐derived small RNAs (tsRNAs) function in digestive cancers across three scales: intracellular translational and metabolic control, extracellular vesicle–mediated immune remodeling, and systemic and host–microbe communication. This review organizes these mechanisms by evidence strength, from well‐established intracellular roles to emerging ...
Wang Xitan, Li Han
wiley   +1 more source

How muscle ageing affects rapid goal-directed movement: mechanistic insights from a simple model. [PDF]

PLoS Comput Biol
Polet DT, Richards CT.
europepmc   +1 more source

Changes in gastrointestinal motility and gut hormone secretion after Roux‐en‐Y gastric bypass and sleeve gastrectomy for individuals with severe obesity

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary Background Bariatric surgery is very effective in long‐term weight management. The present study was undertaken to investigate the short‐term effects of sleeve gastrectomy (SG) and of Roux‐en‐Y gastric bypass (RYGB) on (a) gastrointestinal (GI) motility, that is gastric emptying and oro‐cecal transit time and (b) secretion of regulatory gut ...
Jennifer A. Wilbrink, Mark van Avesaat, Simon W. Nienhuijs, Arnold Stronkhorst, Ad A. M. Masclee   +4 more
wiley   +1 more source

Lower-limb strength and power characteristics in relation to 180° change of direction ability in elite female basketball players. [PDF]

Front Sports Act Living
Ogata H, Yamashita D, Nishikawa N, Yokozawa T, Hoshikawa M.   +4 more
europepmc   +1 more source

The specifics of non‐routine task changes: A granular approach

Contemporary Economic Policy, EarlyView.
Abstract This paper estimates granular specific non‐routine tasks and examines employment reallocation across those tasks in the United States. Employment shifts into decision‐making, technology, and information‐related tasks account for 90% of high‐wage employment growth.
Carol A. Scotese
wiley   +1 more source