Results 181 to 190 of about 9,753 (239)

Acute Change of Footwear Limits Performance and Alters Foot Strike Patterns During Anticipated and Unanticipated 90° Change of Direction. [PDF]

J Foot Ankle Res
Siegel SD, Sproll M, Warneke K, Mason J, Zech A.   +4 more
europepmc   +1 more source

Slow Transit Constipation: Pathophysiological Perspectives and Management Updates

Journal of Digestive Diseases, EarlyView.
Slow transit constipation (STC) is a complex neuromuscular disorder driven by interstitial cells of Cajal (ICCs) loss and enteric neuropathy. Diagnosis relies on objective transit testing while excluding pelvic floor dysfunction. Management follows a stepwise, phenotype‐driven approach, progressing from conventional laxatives to emerging targeted ...
Athanasios Syllaios, Stavros P. Papadakos, Alexandros Ioannou, Maximos Frountzas, Dimosthenis Michelakis, Dimitrios Patsouras, Spyridon Dritsas, Manousos‐Georgios Pramateftakis, Dimitrios Schizas   +8 more
wiley   +1 more source

Biomechanical Differences Between Ipsilateral and Contralateral Change-Of- Direction Movements Using the Same Planting Foot in Recreational Team Sport Players. [PDF]

J Sports Sci Med
Chen CH, Yeh M, Liu C, Tseng YJ, Lu ST.
europepmc   +1 more source

What is the incidence and clinical significance of dry eye disease in patients treated with immune checkpoint inhibitors? A systematic review and meta‐analysis of ocular immune‐related adverse events

Acta Ophthalmologica, EarlyView.
Abstract Purpose Immune checkpoint inhibitors (ICIs) have transformed cancer therapy but may cause immune‐related adverse events (irAEs), including dry eye disease (DED). This study aimed to quantify the incidence of ICI‐associated DED and to evaluate factors contributing to variability across studies.
Kai‐Yang Chen, Hoi‐Chun Chan, Chi‐Ming Chan   +2 more
wiley   +1 more source

Development and control of a robotic assistant walking aid for fall risk reduction. [PDF]

Front Robot AI
Naderer M, Kim Y, Kim TH, Kim Y.
europepmc   +1 more source

Can Generative AI support the learning agency of students with disability? A case study of an Australian secondary school

British Journal of Educational Technology, EarlyView.
Abstract Despite increasing interest in using Generative Artificial Intelligence (GenAI) in education, little is known about how students with disability engage with GenAI to support their own learning. This study investigates the potential of ChatGPT to support the learning agency of adolescents with disability in a secondary science classroom in ...
Natasha Anne Rappa, Karen P. Nonis, Kok‐Sing Tang, Grant Cooper, Martin Cooper, Craig Sims   +5 more
wiley   +1 more source

Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt

British Journal of Pharmacology, EarlyView.
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown, Alan Armstrong, David J. Mann   +2 more
wiley   +1 more source

Is There a Performance-Injury Conflict Between Maximum Horizontal Deceleration and Surrogates of Noncontact Anterior Cruciate Ligament Injury? [PDF]

Eur J Sport Sci
Lin J, Dos'Santos T, Li W, Wang X, Turner A.   +4 more
europepmc   +1 more source

Comprehensive transduceromic profiling of NOP receptor ligands at different Gα subunits

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose The nociceptin/orphanin FQ (N/OFQ) peptide receptor (NOP) is an opioid receptor family member with distinct pharmacology and broad therapeutic potential. NOP receptors regulate functions such as nociception, stress reactivity, reward, mood, autonomic tone, immunity and sleep/wake cycle.
Davide Malfacini, Riccardo Camilotto, Michele Maritan, Erika Morrone, Stephen Afriyie Boateng, Anna Vacilotto, Salvatore Pacifico, Remo Guerrini, Nurulain T. Zaveri, Girolamo Calo'   +9 more
wiley   +1 more source

Doctor, when can I drive? - Influence of muscle weakness of dorsal flexors and plantar flexors from the ankle joint on driving ability. [PDF]

BMC Musculoskelet Disord
Schoeps D, Prost M, Hilsmann F, Lakomek F, Schiffner E, Jungbluth P, Scheyerer MJ, Windolf J, Latz D.   +8 more
europepmc   +1 more source