Results 31 to 40 of about 35,838 (299)

Quantifying the impact of non-adherence to drug therapy: a technical note concerning an application of a branch and bound algorithm [PDF]

open access: yes, 2008
Pharmacokinetic models typically rely on a key assumption that patients take their medication as prescribed, whereas this is often not the case. We present a branch and bound algorithm that can be used to estimate the time-varying probability that ...
Christina Pagel   +7 more
core   +1 more source

An Effective Branch and Bound Algorithm for Minimax Linear Fractional Programming

open access: yesJournal of Applied Mathematics, 2014
An effective branch and bound algorithm is proposed for globally solving minimax linear fractional programming problem (MLFP). In this algorithm, the lower bounds are computed during the branch and bound search by solving a sequence of linear relaxation ...
Hong-Wei Jiao   +2 more
doaj   +1 more source

Integrated Design of Cellular Production System Using Branch and Bound Algorithm

open access: yesDiscrete Dynamics in Nature and Society, 2022
Most research done on the design of cellular production systems also has examined one of the main areas of design including cell formation, cellular layout, and material handling.
Roohallah Ranjbar   +3 more
doaj   +1 more source

Scheduling of Software Test to Minimize the Total Completion Time

open access: yesMathematics, 2023
This paper investigates a single-machine scheduling problem of a software test with shared common setup operations. Each job has a corresponding set of setup operations, and the job cannot be executed unless its setups are completed. If two jobs have the
Man-Ting Chao, Bertrand M. T. Lin
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

An interior point algorithm for minimum sum-of-squares clustering [PDF]

open access: yes, 2000
Copyright @ 2000 SIAM PublicationsAn exact algorithm is proposed for minimum sum-of-squares nonhierarchical clustering, i.e., for partitioning a given set of points from a Euclidean m-space into a given number of clusters in order to minimize the sum of ...
Du Merle, O   +11 more
core   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Combining Interval Branch and Bound and Stochastic Search

open access: yesAbstract and Applied Analysis, 2014
This paper presents global optimization algorithms that incorporate the idea of an interval branch and bound and the stochastic search algorithms.
Dhiranuch Bunnag
doaj   +1 more source

Quantity decisions of two-stage competitive location model based on different location modes

open access: yesComplex & Intelligent Systems, 2021
The facility location of a competing firm in a market has great importance in supply chain management. The two-stage competitive location model formulates the decision process of an entrant firm facing both location and price competition.
Yadong Li, Xuemei Li
doaj   +1 more source

An Approach for Autonomous Feeding Robot Path Planning in Poultry Smart Farm

open access: yesAnimals, 2022
In order to solve the problems of poor feeding environment, untimely feeding and high labor demand in poultry smart farms, the development of feeding robots is imminent, while the research on path planning algorithms is an important part of developing ...
Yanjun Zhang   +5 more
doaj   +1 more source

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