Results 51 to 60 of about 141,288 (266)
Balanced vehicle routing: Polyhedral analysis and branch-and-cut algorithm [PDF]
European Journal of Operational Research, 2019 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Tolga Bektaş +3 more
openaire +4 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
The structure of the South-Central-Pyrenean fold and thrust belt as constrained by subsurface data
Geologica Acta, 2018 The interpretation of the available seismic lines of the South-Central-Pyrenean fold and thrust belt, conveniently tied with the exploration wells, define the main structural features of this realm of the Pyrenees.
J.A. MUÑOZ +6 more
doaj
The Fruitless Branch and the Eternal Security of the Believer
E-Journal of Religious and Theological Studies, 2022 The quest for the identification of the fruitless branch has been an enduring theological battleground between the Calvinists and the Arminians who argue as to whether or not the removal of the fruitless branch indicates the loss of eternal salvation.
Anthony Yaw Badu +1 more
doaj +1 more source
Branch-and-Cut-and-Price for Multi-Agent Pathfinding [PDF]
Proceedings of the Twenty-Eighth International Joint Conference on Artificial Intelligence, 2019 There are currently two broad strategies for optimal Multi-agent Pathfinding (MAPF): (1) search-based methods, which model and solve MAPF directly, and (2) compilation-based solvers, which reduce MAPF to instances of well-known combinatorial problems, and thus, can benefit from advances in solver techniques.
Edward Lam +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Critical evaluation of branch polarity and apical dominance as dictators of colony astogeny in a branching coral. [PDF]
PLoS ONE, 2009 The high morphological resemblance between branching corals and trees, can lead to comparative studies on pattern formation traits, best exemplified in plants and in some cnidarians.
Lee Shaish, Baruch Rinkevich
doaj +1 more source