Results 31 to 40 of about 25,776 (266)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

PENENTUAN RUTE KENDARAAN PADA SISTEM DISTRIBUSI LOGISTIK PASCA BENCANA (STUDI KASUS)

open access: yesJurnal Manajemen Industri dan Logistik, 2018
The success indicators of disaster mitigation can be seen from the disaster logistics system. Effective and efficient distribution network can make a good disaster logistics system.
Andriansyah Andriansyah   +1 more
doaj   +1 more source

Distribution Route Optimization of Zakat Al-Fitr Based on the Branch-and-Bound Algorithm

open access: yesJTAM (Jurnal Teori dan Aplikasi Matematika), 2023
The short interval between the collecting and distribution of zakat al-fitr is a recurring issue. As a result, ‘amil does not always pay attention to the ideal route, leading in inefficient transportation expenditures.
Noor Saif Muhammad Mussafi
doaj   +1 more source

An interval-matrix branch-and-bound algorithm for bounding eigenvalues

open access: yesOptimization Methods and Software, 2016
We present and explore the behaviour of a branch-and-bound algorithm for calculating valid bounds on the kth largest eigenvalue of a symmetric interval matrix. Branching on the interval elements of the matrix takes place in conjunction with the application of Rohn's method (an interval extension of Weyl's theorem) in order to obtain valid outer bounds ...
Dimitrios Nerantzis, Claire S. Adjiman
openaire   +2 more sources

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

A new branch and bound algorithm for minimax ratios problems

open access: yesOpen Mathematics, 2017
This study presents an efficient branch and bound algorithm for globally solving the minimax fractional programming problem (MFP). By introducing an auxiliary variable, an equivalent problem is firstly constructed and the convex relaxation programming ...
Zhao Yingfeng, Liu Sanyang, Jiao Hongwei
doaj   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif   +17 more
wiley   +1 more source

Affecting the Properties of Copper–Graphene Electroconductive Composite by Severe Plastic Deformation

open access: yesAdvanced Engineering Materials, EarlyView.
Copper‐based composites enhanced with carbon feature convenient mechanical properties and favorable electric conductivity. Processing via deformation and thermomechanical treatments can introduce advantageous microstructures further enhancing their performance. Herein, copper–graphene powder‐based composites are directly consolidated via rotary swaging
Radim Kocich   +3 more
wiley   +1 more source

A Global Optimization Algorithm for Solving Linearly Constrained Quadratic Fractional Problems

open access: yesMathematics, 2021
This paper first proposes a new and enhanced second order cone programming relaxation using the simultaneous matrix diagonalization technique for the linearly constrained quadratic fractional programming problem.
Zhijun Xu, Jing Zhou
doaj   +1 more source

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