Results 31 to 40 of about 41,581 (262)

A Branch-and-Cut algorithm for graph coloring

open access: yesDiscrete Applied Mathematics, 2006
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Méndez-Díaz, I., Zabala, P.
openaire   +4 more sources

Learning to Configure Separators in Branch-and-Cut

open access: yesAdvances in Neural Information Processing Systems 36, 2023
Cutting planes are crucial in solving mixed integer linear programs (MILP) as they facilitate bound improvements on the optimal solution. Modern MILP solvers rely on a variety of separators to generate a diverse set of cutting planes by invoking the separators frequently during the solving process.
Sirui Li   +3 more
openaire   +3 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Branch‐cut cosmology and the Bekenstein Criterion

open access: yesAstronomische Nachrichten, 2022
AbstractIn this contribution, we address the implications of the Bekenstein Criterion in the branch‐cut cosmology. The impossibility of packaging energy and entropy according to the Bekenstein Criterion in a finite size makes the transition phase of the branch‐cut cosmology very peculiar, imposing a topological leap between the contraction and ...
José A. de Freitas Pacheco   +4 more
openaire   +2 more sources

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Multi-objective Optimization of Peak Cutting Force and Cutting Energy Consumption in Cutting of Caragana korshinskii Branches

open access: yesBioResources, 2022
Caragana korshinskii (C.K.) flat stubble residue is an abundant biomass energy source in China. Because branch cutting is closely related to the harvesting of forest biomass, it is practical for forestry production and ecological development to ...
Yaoyao Gao   +5 more
doaj   +2 more sources

PENERAPAN BRANCH AND BOUND ALGORITHM DALAM OPTIMALISASI PRODUKSI ROTI

open access: yesE-Jurnal Matematika, 2016
Companies which engaged in production activities such as Ramadhan Bakery would want optimal profit in their every production. The aim of this study was to find optimal profit and optimal combination of bread production (original chocolate bread, extra ...
GEDE SURYAWAN   +2 more
doaj   +1 more source

The Fruitless Branch and the Eternal Security of the Believer

open access: yesE-Journal of Religious and Theological Studies, 2022
The quest for the identification of the fruitless branch has been an enduring theological battleground between the Calvinists and the Arminians who argue as to whether or not the removal of the fruitless branch indicates the loss of eternal salvation.
Anthony Yaw Badu   +1 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

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