Results 41 to 50 of about 1,037,081 (304)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
BioResources, 2022 Caragana korshinskii (C.K.) flat stubble residue is an abundant biomass energy source in China. Because branch cutting is closely related to the harvesting of forest biomass, it is practical for forestry production and ecological development to ...
Yaoyao Gao +5 more
doaj +2 more sources
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
PENERAPAN BRANCH AND BOUND ALGORITHM DALAM OPTIMALISASI PRODUKSI ROTI
E-Jurnal Matematika, 2016 Companies which engaged in production activities such as Ramadhan Bakery would want optimal profit in their every production. The aim of this study was to find optimal profit and optimal combination of bread production (original chocolate bread, extra ...
GEDE SURYAWAN +2 more
doaj +1 more source
The Fruitless Branch and the Eternal Security of the Believer
E-Journal of Religious and Theological Studies, 2022 The quest for the identification of the fruitless branch has been an enduring theological battleground between the Calvinists and the Arminians who argue as to whether or not the removal of the fruitless branch indicates the loss of eternal salvation.
Anthony Yaw Badu +1 more
doaj +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Leaf Pruning End-Effector for Adaptive Positioning at the Branch–Stem Junction of Tomato Plants
AgricultureTo address the needs of mechanized tomato leaf pruning, this paper presents the design of an end-effector capable of adaptive positioning at the base of the branch.
Yuhuan Sun +6 more
doaj +1 more source
Natural Gas Industry B, 2017 At present, the aeration-assisted cutting-carrying technology is faced with complexities in the drilling of CBM multi-branch horizontal wells. For example, the aerating pressure is hardly maintained, and the borehole instability may happen.
Yong Yang +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source