Biosynthesis, regulation, and engineering of microbially produced branched biofuels
Biotechnology for Biofuels, 2019 The steadily increasing demand on transportation fuels calls for renewable fuel replacements. This has attracted a growing amount of research to develop advanced biofuels that have similar physical, chemical, and combustion properties with petroleum ...
Wenqin Bai +3 more
doaj +1 more source
Transcriptomic-metabolomic reprogramming in EGFR-mutant NSCLC early adaptive drug escape linking TGFβ2-bioenergetics-mitochondrial priming. [PDF]
, 2016 The impact of EGFR-mutant NSCLC precision therapy is limited by acquired resistance despite initial excellent response. Classic studies of EGFR-mutant clinical resistance to precision therapy were based on tumor rebiopsies late during clinical tumor ...
Bagai, Rakesh +14 more
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Therapeutic Effect of Targeting Branched-Chain Amino Acid Catabolic Flux in Pressure-Overload Induced Heart Failure. [PDF]
, 2019 Background Branched-chain amino acid (BCAA) catabolic defect is an emerging metabolic hallmark in failing hearts in human and animal models. The therapeutic impact of targeting BCAA catabolic flux under pathological conditions remains understudied ...
Chen, Mengping +8 more
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mSystemsClostridium thermocellum is a leading candidate for consolidated bioprocessing of lignocellulosic biomass into biofuels due to its native cellulolytic capabilities. Beyond ethanol, C.
Eashant Thusoo +6 more
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The biological functions and metabolic pathways of valine in swine
Journal of Animal Science and Biotechnology, 2023 Valine is an essential amino acid and a type of branched-chain amino acid. Due to the involvement of branched-chain amino acids in various metabolic pathways, there has been a surge of interests in valine nutrition and its role in animal physiology.
Chuni Wang +6 more
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Flow-injection of branched polymers inside nanopores
, 2005 Flexible chains (linear or branched) can be forced to enter into a narrow capillary by using a hydrodynamic flow. Here, we correct our earlier description of this problem by considering the progressive nature of the suction process.
Brochard-Wyart, Françoise +3 more
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Metformin promotes lifespan through mitohormesis via the peroxiredoxin PRDX-2 [PDF]
, 2014 The antiglycemic drug metformin, widely prescribed as first-line treatment of type II diabetes mellitus, has lifespan-extending properties. Precisely how this is achieved remains unclear.
Billen, Johan +8 more
core +1 more source
eLife, 2019 We find that variation in the dbt-1 gene underlies natural differences in Caenorhabditis elegans responses to the toxin arsenic. This gene encodes the E2 subunit of the branched-chain α-keto acid dehydrogenase (BCKDH) complex, a core component of ...
Stefan Zdraljevic +9 more
doaj +1 more source
Conditions stimulating neutral detergent fiber degradation by dosing branched-chain volatile fatty acids. III: Relation with solid passage rate and pH on prokaryotic fatty acid profile and community in continuous culture [PDF]
, 2021 Y. Roman-Garcia +6 more
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Characterization and epitope mapping of human monoclonal antibodies to PDC-E2, the immunodominant autoantigen of primary biliary cirrhosis [PDF]
, 1992 Further to define the epitopes of PDC-E2, the major autoantigen in primary biliary cirrhosis (PBC), we have developed and characterized five human monoclonal antibodies. These antibodies were derived by fusing a regional hepatic lymph node from a patient
Bassendine +49 more
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