Advanced Science, EarlyView.A sulfated polysaccharide (SCP) from Cyclocarya paliurus alleviates ulcerative colitis by reshaping the gut microbiome. This remodeled microbiota orchestrates the upregulation of the host‐derived lipid 12‐HEPE, which directly inhibits the TLR4/NF‐κB pathway to suppress inflammation.
Xianxiang Chen +11 more
wiley +1 more source
Complex Adsorption Pattern Formation in Drying BSA-NaCl Droplets: Experimental Study. [PDF]
Int J Mol SciBorshchegovskaya P +9 more
europepmc +1 more source
Inhibitory Decay and Supercritical Brain Dynamics During Sleep Deprivation
Advanced Science, EarlyView.Sleep deprivation progressively shifts human brain dynamics from near‐critical toward supercritical states, as revealed by neuronal avalanche analysis of resting‐state fMRI. These changes track subjective sleep pressure rather than vigilance lapses and show marked network heterogeneity. A circuit model suggests that reduced inhibitory efficacy provides
Dai Zhang +6 more
wiley +1 more source
Tuning Thermochemistry Behavior of Coal Gasification Fine Ash via Alkyl Chain-Length-Dependent Surface Functionalization: Mechanisms and Structure-Property Relationships. [PDF]
MoleculesJiao L, Yu H, Li Y, Chen Y, Li J, Li X.
europepmc +1 more source
Mixing‐Driven Defects and Composition Evolution in Multi‐Material Metal Additive Manufacturing
Advanced Science, EarlyView.Operando synchrotron X‐ray imaging coupled with high‐fidelity multiphysics modeling uncovers how inter‐material mixing reshapes keyhole dynamics and drives distinct pore‐formation pathways in multi‐material laser powder bed fusion (LPBF). Composition‐dependent instabilities trigger defects, whereas rescanning suppresses porosity and homogenizes Cu ...
Zhilang Zhang +5 more
wiley +1 more source
Polymers and Chemical Composition of Hardwood and Softwood (Bark, Sapwood, and Heartwood) for Biofuel Production: A Comprehensive Review. [PDF]
Polymers (Basel)Aniza R, Petrissans A, Petrissans M.
europepmc +1 more source
Advanced Science, EarlyView.Dual targeting of ANGPTL3 and IL‐33/ST2 attenuates diabetic kidney disease by reprogramming lipid–inflammatory crosstalk. This strategy reduces renal lipotoxicity, suppresses inflammatory activation, and limits fibrotic remodeling, thereby preserving kidney structure and function and highlighting a mechanism‐guided therapeutic approach for metabolic ...
Zhuojin Li +8 more
wiley +1 more source
Metabolomics in Motion: Translating Molecular Signatures into Clinical Impact. [PDF]
MetabolitesKounatidis D, Mourouzis I.
europepmc +1 more source
Advanced Science, EarlyView.This review explores the convergence of artificial intelligence technologies in modeling drug–drug and drug–target interactions. By evaluating advanced feature engineering, architectural innovations, and learning paradigms reveals shared evolutionary trends and critical challenges, such as cold‐start settings and shortcut learning.
Xin Sun, Tong Wang
wiley +1 more source
Exact Inference on Gaussian Graphical Models of Arbitrary Topology using Path-Sums
, 2014 We present the path-sum formulation for exact statistical inference of marginals on Gaussian graphical models of arbitrary topology. The path-sum formulation gives the covariance between each pair of variables as a branched continued fraction of finite ...
Thwaite, SJ +7 more
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