Results 141 to 150 of about 202,833 (274)

Glycolysis‐Derived Lactate Induces ACSL4 Expression and Lactylation to Activate Ferroptosis during Intervertebral Disc Degeneration

Advanced Science, EarlyView.
Glycolysis‐derived lactate activates nucleus pulposus cell ferroptosis via Histon H3K18la‐mediated ACSL4 transcription and ACSL4 lactylation and aggravate intervertebral disc degeneration. Inhibiting glycolysis via gene silencing or chemical intervention reduces the production of lactate and ameliorates ferroptosis activation and nucleus pulposus ...
Kaiqiang Sun, Yangyang Shi, Chen Yan, Shunmin Wang, Linhui Han, Fudong Li, Ximing Xu, Yuan Wang, Jingchuan Sun, Zijian Kang, Jiangang Shi   +10 more
wiley   +1 more source

Morphological Evolution: Bioinspired Methods for Analyzing Bioinspired Robots. [PDF]

Front Robot AI, 2021
Aaron E, Hawthorne-Madell J, Livingston K, Long JH.   +3 more
europepmc   +1 more source

Shape‐Selective Molecular Separations Enabled by Rigid and Interconnected Confinements Engineered in Conjugated Microporous Polymer Membranes

Advanced Science, EarlyView.
Conjugated microporous polymer membranes with narrowly distributed network pores are prepared by diffusion‐modulated electropolymerization. This approach precisely controls the monomer diffusion and coupling processes, regulating the crosslinking degree to prevent broad aggregate pores and microporous defects.
Yanqiu Lu, Hao Deng, Liling Zhang, Yong Wang, Sui Zhang   +4 more
wiley   +1 more source

Dynamic Pathophysiological Insight into the Brain by NIR‐II Imaging

Advanced Science, Volume 12, Issue 16, April 24, 2025.
The functional integration of benefits from small semiconducting dyes and biocompatible serum proteins ushered in a new frontier of deep wide‐field in vivo imaging technique, affording valuable pathophysiological insight into the functioning of neurovascular unit in space and time.
Si Chen, Hao Chen, Xinxin Li, Shuqing He, Kangquan Shou, Kun Qian, Zhao Fang, Feng Gu, Baisong Chang, Zhen Cheng   +9 more
wiley   +1 more source

An experimental platform for stochastic analyses of single serotonergic fibers in the mouse brain. [PDF]

Front Neurosci, 2023
Mays KC, Haiman JH, Janušonis S.
europepmc   +1 more source

Survival Probability of the Branching Random Walk Killed Below a Linear Boundary [PDF]

, 2011
Jean Bérard, Jean-Baptiste Gouéré
openalex   +1 more source

S‐ketamine Alleviates Neuroinflammation and Attenuates Lipopolysaccharide‐Induced Depression Via Targeting SIRT2

Advanced Science, EarlyView.
S‐ketamine binds directly to SIRT2, facilitating its interaction with NF‐κB p65. This interaction reduces the acetylation of NF‐κB p65 and inhibits its activation, thereby exerting anti‐inflammatory and antidepressant effects. Created by BioRender.
Cong Lin, Xiaoxuan Zhou, Mingqi Li, Cong Zhang, Haojiang Zhai, Haohong Li, Hongshuang Wang, Xiaohui Wang   +7 more
wiley   +1 more source

A Remark on Localization for Branching Random Walks in Random Environment [PDF]

, 2011
Hadrian Heil, Makoto Nakashima
openalex   +1 more source

Origins, Dispersal, and Impact: Bidirectional Introgression Between Chinese and European Pig Populations

Advanced Science, EarlyView.
This study investigates bidirectional introgression between Chinese and European pig populations, revealing 3558 introgressed genomic segments and 30 structural variations. Analysis of the BMP2 region suggests its role in body size enhancement. By integrating ancient and modern genomes, the study highlights the impact of introgression on genetic ...
Yibin Qiu, Langqing Liu, Min Huang, Donglin Ruan, Rongrong Ding, Zebin Zhang, Enqin Zheng, Shiyuan Wang, Shaoxiong Deng, Xianglun Meng, Xinyan Cheng, Jiaxin Shi, Yingshan Yang, Fuchen Zhou, Sixiu Huang, Huaqiang Yang, Zicong Li, Gengyuan Cai, Zhenfang Wu, Jie Yang   +19 more
wiley   +1 more source

Investigation of cell development and tissue structure network based on natural Language processing of scRNA-seq data. [PDF]

J Transl Med
Wei S, Lu Y, Wang P, Li Q, Shuai J, Zhao Q, Lin H, Peng Y.   +7 more
europepmc   +1 more source