Results 111 to 120 of about 398,602 (339)
Molecular Oncology, EarlyView.This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini +10 more
wiley +1 more source
Brand market positions estimation and defining the strategic targets of its development [PDF]
Marketing i Menedžment Innovacij, 2010 In this article the author generalizes the concept of brand characteristics which influenceits profitability and market positions. An approach to brand market positions estimation anddefining the strategic targets of its development is proposed.Keywords:
S.M. Makhnusha
doaj
The impact of step-down line extension on consumer-brand relationships: A risky strategy for luxury brands [PDF]
, 2011 Cahiers de recherche 2011-07 E3This paper analyzes the role of the brand concept (luxury vs. non-luxury) in the impact of step-down line extension on consumer-brand relationships.
Magnoni, F. +2 more
core +2 more sources
Brand Extension Impact on Parent Brand Equity: A European Perspective : Cross-cultural Analysis of Extending a Football League Brand to eSports [PDF]
, 2020 This research explores whether the dimensions of parent brand equity affect brand extension success and on what scale. Furthermore, brand extension’s impact on parent brand equity is analysed.
Sallinen, Juuso Janne Johannes
core
Difference in Extended Products Evaluation by Consumer Innovativeness and Similarity of Product Category for Apparel Brand Extension [PDF]
, 2009 Young-Ju Rhee
openalex +1 more source
Molecular Oncology, EarlyView.Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka +10 more
wiley +1 more source
Is cross-category brand loyalty determined by risk aversion? [PDF]
The need to understand and leverage consumer-brand bonds has become critical in a marketplace characterized by increasing unpredictability, diminishing product differentiation, and heightened competitive pressure.
Lutz Hildebrandt, Nadja Silberhorn
core
Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma
Molecular Oncology, EarlyView.This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu +15 more
wiley +1 more source
BRAND EXTENSIONS IN CONFECTIONARY; THE MARS DELIGHT [PDF]
, 2005 The concept of brand extension has been considered for several decades, drawing of work by Tauber (1981). Effective branding requires an understanding of areas such as segmentation, targeting and positioning which are critical in developing a successful ...
Lane, D, sutcliffe, A
core
Molecular Oncology, EarlyView.There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source