Results 291 to 300 of about 953,712 (378)

Consideration of ethnic differences in approvals for anti‐HIV medicines in Japan: Evaluation based on pharmacokinetic studies and post‐marketing data

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
More than 30 anti‐HIV drugs have been approved in Japan using data from dossiers submitted to the United States or European regulatory authorities since 1998. These drugs were approved with the same dosage and administration regimes as in the United States and Europe, using data from pivotal studies that rarely included any Japanese patients, whereas ...
Rumiko Shimazawa, Masayuki Ikeda
wiley   +1 more source

Medications, epilepsy and climate change: Added layers of complexity

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Climate change—the global crisis with pervasive health impacts—has adverse consequences for people with epilepsy (PWE) who have low quality of life due to poor seizure control, socioeconomic disadvantages and comorbidities. This review focuses on the potential effects of climate change on the pharmacological characteristics of antiseizure medications ...
Medine I. Gulcebi   +2 more
wiley   +1 more source

Oral vancomycin solution is superior to capsule in inducing clinical biomarker and endoscopic remission in children with atypical ulcerative colitis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Atypical colitis (presenting reverse gradient colitis, backwash ileitis or rectal sparing) is associated with primary sclerosing cholangitis–ulcerative colitis (PSC). Oral vancomycin has been used to manage paediatric atypical colitis with/without confirmed PSC. Different preparations had shown different efficacy.
Laura Räisänen   +4 more
wiley   +1 more source

The impact of a preprescribing formative assessment on learning in final‐year medical students using hospital inpatient electronic prescribing systems

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Graduating medical students consistently report being unprepared for the complexity of prescribing in clinical practice. Current clinical prescribing teaching and authentic assessment are limited due to patient safety concerns. We aimed to examine the educational utility of supervised preprescribing as a learning process and potential authentic ...
Kellie A. Charles   +7 more
wiley   +1 more source

Social franchising in healthcare: a systematic review and narrative synthesis of implementation and outcomes. [PDF]

open access: yesBMJ Glob Health
Rahman MH   +10 more
europepmc   +1 more source

Status of oncology drugs with a conditional approval: A cross‐sectional comparison of the Food and Drug Administration and Health Canada

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims This study looks at the status of the same drugs conditionally approved by the Food and Drug Administration and Health Canada for the same oncology indication. Methods Lists of oncology drugs with a conditional approval from the Food and Drug Administration and Health Canada were generated and drug pairs with the same indication were matched ...
Joel Lexchin
wiley   +1 more source

Young TPI: empowering animal-free science among the next- generation of scientists. [PDF]

open access: yesFront Toxicol
G Valverde M   +6 more
europepmc   +1 more source

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