More than 30 anti‐HIV drugs have been approved in Japan using data from dossiers submitted to the United States or European regulatory authorities since 1998. These drugs were approved with the same dosage and administration regimes as in the United States and Europe, using data from pivotal studies that rarely included any Japanese patients, whereas ...
Rumiko Shimazawa, Masayuki Ikeda
wiley +1 more source
Stakeholders' perceptions on the role of professional sports clubs in local community health promotion. [PDF]
Brazier J+3 more
europepmc +1 more source
Medications, epilepsy and climate change: Added layers of complexity
Climate change—the global crisis with pervasive health impacts—has adverse consequences for people with epilepsy (PWE) who have low quality of life due to poor seizure control, socioeconomic disadvantages and comorbidities. This review focuses on the potential effects of climate change on the pharmacological characteristics of antiseizure medications ...
Medine I. Gulcebi+2 more
wiley +1 more source
The impact of dynamic marketing capabilities (DMCs) and strategic information management (SIM) on international start-up success: A meta narrative analysis. [PDF]
Stefia CM+3 more
europepmc +1 more source
Aims Atypical colitis (presenting reverse gradient colitis, backwash ileitis or rectal sparing) is associated with primary sclerosing cholangitis–ulcerative colitis (PSC). Oral vancomycin has been used to manage paediatric atypical colitis with/without confirmed PSC. Different preparations had shown different efficacy.
Laura Räisänen+4 more
wiley +1 more source
Is sports-branded screening effective in identifying adults at greatest risk of developing cardiovascular disease: a convergent parallel mixed-methods design to identify adults at greatest risk of developing cardiovascular disease using an opportunistic sports-branded health screening approach in the community. [PDF]
Jones ID+9 more
europepmc +1 more source
Aims Graduating medical students consistently report being unprepared for the complexity of prescribing in clinical practice. Current clinical prescribing teaching and authentic assessment are limited due to patient safety concerns. We aimed to examine the educational utility of supervised preprescribing as a learning process and potential authentic ...
Kellie A. Charles+7 more
wiley +1 more source
Social franchising in healthcare: a systematic review and narrative synthesis of implementation and outcomes. [PDF]
Rahman MH+10 more
europepmc +1 more source
Aims This study looks at the status of the same drugs conditionally approved by the Food and Drug Administration and Health Canada for the same oncology indication. Methods Lists of oncology drugs with a conditional approval from the Food and Drug Administration and Health Canada were generated and drug pairs with the same indication were matched ...
Joel Lexchin
wiley +1 more source
Young TPI: empowering animal-free science among the next- generation of scientists. [PDF]
G Valverde M+6 more
europepmc +1 more source