Results 21 to 30 of about 316 (120)

Towards an ‘absolute’ timing of biostratigraphic and environmental phases from the Saalian late glacial to the Weichselian pleniglacial in central Europe—Insights from a lacustrine succession in Lichtenberg, northern Germany

Boreas, EarlyView.
Palynological records are central to the biostratigraphic subdivision of the Late Pleistocene in central Europe. Yet many interglacial and interstadial phases—such as the Eemian, Brörup and Odderade—remain only poorly constrained in time due to limited numerical dating.
Michael Hein, Thomas Kasper, Alexis Badai Samudra, Martin Theuerkauf, Markus Lothar Fischer, Neda Rahimzadeh, Maria Sekar Proborukmi, Sonja Rigterink, Agnieszka Gruszczyńska, Christian Zeeden, Simon Parfitt, David John Horne, Lucy Roberts, Dustin White, Lisa Brogmus, Hans von Suchodoletz, Tobias Lauer, Marcel Weiss, David Colin Tanner, Brigitte Urban   +19 more
wiley   +1 more source

Cardiac surveillance in immune checkpoint inhibitor therapy: Insights from the Essen Cardio‐oncology Registry

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Immune checkpoint inhibitors (ICI) have revolutionized cancer therapy, offering improvements in survival across various malignancies. However, their toxicities pose a major challenge for cardio‐oncology units. Despite their growing importance, data on effectiveness of such specialized units in mitigating ICI‐associated ...
Elias Haj‐Yehia, Lisa Zimmer, Lena Lampe, Dimitra Vlachopoulou, Matthias Totzeck, Tienush Rassaf, Raluca I. Mincu   +6 more
wiley   +1 more source

Ketogenic Diet Alleviates Colorectal Cancer by Attenuating Macrophage M2 Polarisation Triggered by Oncometabolite MMA Derived From the Gut Microbiota

Cell Proliferation, EarlyView.
Proposed mechanism of the ketogenic diet‐microbiota‐MMA‐immune axis in CRC. (Part 1) A ketogenic diet remodels gut microbiota homeostasis by depleting MMA‐producing bacteria, thereby reducing the accumulation of the oncometabolite (MMA). (Part 2) At the molecular level, MMA acts as a ligand that binds to Rap1, activating the downstream MAPK/ERK ...
Yang Lu, Bo Shi, Jinmiao Chen, Huihui Yao, Xiuwei Mi, Minke Shao, Yiyuan Zhao, Lijun Meng, Qingliang Tai, Junjie Chen, Xinyu Shi, Diyuan Zhou, Yizhou Yao, Songbing He   +13 more
wiley   +1 more source

Dentine Regeneration With Calcium Strontium Silicate: In Vitro Odontogenic Differentiation, Antimicrobial Activity, Immunomodulation and In Vivo Pulpotomy in Rat Molars

International Endodontic Journal, EarlyView.
ABSTRACT Aim This study examined the in vitro and in vivo performance of calcium strontium silicate (CSR) as a novel biomaterial for vital pulp therapy (VPT), assessing its odontogenic differentiation, antibacterial activity, immunomodulation, inflammatory response and dentine regeneration potential compared to calcium silicate (CS) and Mineral ...
Mohamed Mahmoud Abdalla, Vidhyashree Rajasekar, Heba Ahmed, Mengyu Huang, Cynthia Kar Yung Yiu   +4 more
wiley   +1 more source

Improving Digital Transformation Outcomes and Pace: The Role of the Board and C‐Suite in Reducing Transformation Friction

Information Systems Journal, EarlyView.
ABSTRACT Most organisations are confronting a dilemma: the need to embark on digital transformation to be competitive and sustainable versus the inherently high costs and extremely high risks involved. Lack of executive support has long been identified as a leading cause of project failure, including digital transformation projects.
Natalie Smith, Andrew Burton‐Jones
wiley   +1 more source

Conservation genomics of Pecos pupfish (Cyprinodon pecosensis)

Journal of Fish Biology, EarlyView.
Abstract The Pecos pupfish, Cyprinodon pecosensis, is an imperilled freshwater fish found in arid regions of Texas and New Mexico (USA). The species faces multiple challenges to persistence including reductions in suitable habitat, water shortages, as well as hybridization and competition with an introduced congener (sheepshead minnow, C.
Elizabeth P. Dolan, Andrew T. Fields, Megan G. Bean, Robyn R. Doege, Joanna L. Hatt, Kevin W. Conway, David S. Portnoy   +6 more
wiley   +1 more source

Dissecting the genetic basis of climatic adaptation in wild relatives (Malus baccata) for climate‐resilient apple breeding

Journal of Integrative Plant Biology, EarlyView.
This comprehensive map of genetic variation in wild apple (Malus baccata) and set of key genes associated with adaptation to temperature, precipitation, and soil properties establishes a foundation for breeding climate‐resilient apple cultivars and conserving the genetic resources of wild crop relatives.
Ying Su, Yani Hao, Xuejing Cao, Lin Wang, Zhiqi Xu, Fan Zhang, Zhiyao Ma, Xu Wang, Jiacui Li, Tianrong Fan, Ruoyan Zhao, Zhongqi Liu, Wenrui Wang, Yingchun Zhang, Xuanwen Yang, Sifan Yang, Dajiang Wang, Kun Wang, Simiao Sun, Zichen Li, Wen Tian, Yanming Sun, Zhao Liu, Yanshuai Xu, Hua Xiao, Yanling Peng, Xiaodong Xu, Ruirui Liu, Xinmin Tian, Yongfeng Zhou, Yuan Gao   +30 more
wiley   +1 more source

Categorical Atypicality and Evaluation Accuracy: Who Make More Accurate Evaluations of Atypical Firms?

Journal of Management Studies, EarlyView.
Abstract Prior literature on market categories and identities focuses primarily on whether categorical atypicality leads to positive or negative evaluation; however, much less is known about whether the evaluation is accurate or not. While it is important for producers to know if atypicality is penalized or rewarded, audiences are also concerned about ...
Pengfei Wang, Jingjiang Liu
wiley   +1 more source

Effective When Distinctive: The Role of Phonetic Similarity in Nested Dependency Learning Across Preschool Years

Language Learning, EarlyView.
Abstract Parallel tracking of distant relations between speech elements, so‐called nonadjacent dependencies (NADs), is crucial in language development but computationally demanding and acquired only in late preschool years. As processing of single NADs is facilitated when dependent elements are perceptually similar, we investigated how phonetic ...
Dimitra‐Maria Kandia, Angela D. Friederici, Jutta L. Mueller, Claudia Männel   +3 more
wiley   +1 more source

From Threat to Challenge: Addressing Resistance to Diversity Through Holistic Diversity Previews and Tools

Public Administration Review, EarlyView.
ABSTRACT Support for diversity, equity, and inclusion (DEI) is a core public value and central to public administration. Yet, as diversity is realized through shifts in employee representation, organizational norms, and implementation practices, some members of socially privileged groups (e.g., White employees, men) experience discomfort and anxiety in
Ines Jurcevic, Felix Danbold, Miguel M. Unzueta   +2 more
wiley   +1 more source