Results 21 to 30 of about 2,363,675 (310)

Assessment of Energy Centres in Brazil: A prospective study for the creation of an integrated energy centre in Brazil [PDF]

, 2019
HEADLINES: • The authors advise the British Embassy to create a Brazil-UK Energy Centre, with legitimacy, independence, and financial sustainability, involving leading stakeholders from the energy sector and academia.
Pinto, João Onofre Pereira, Strapasson, Alexandre, Costa, Hirdan Katarina de Medeiros, Ferreira, Denilson   +3 more
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

New challenges for women workers in Brazil facing the wave of Industry 4.0 technologies [PDF]

, 2022
This paper aims to understand how women’s work tends to be particularly affected by the new wave of Industry 4.0 technologies in Brazil and how public policies could actuate to reduce work gender inequalities throughout this process.
Garcia, Mariana Hansen, Dietrich, Priscila von   +1 more
core   +1 more source

What Is the Molecular Signature of Mind–Body Interventions? A Systematic Review of Gene Expression Changes Induced by Meditation and Related Practices

Frontiers in Immunology, 2017
There is considerable evidence for the effectiveness of mind–body interventions (MBIs) in improving mental and physical health, but the molecular mechanisms of these benefits remain poorly understood.
Ivana Buric, Ivana Buric, Miguel Farias, Jonathan Jong, Christopher Mee, Inti A. Brazil, Inti A. Brazil, Inti A. Brazil, Inti A. Brazil   +8 more
doaj   +1 more source

Diptera, Psychodidae, Phlebotominae Rondani,1840: range extension and new records from lowland Bolivia [PDF]

Check List, 2010
During a field trip to the town of El Carmen in de Department of Santa Cruz we captured 108 specimens of Phlebotominae (Diptera: Psychodidae). Among the specimens examined, we found five species of sand fly comprising four genera. Four species (Lutzomyia
Reginaldo Brazil, Wagner Passos, Beatriz Brazil, Miroslav Temeljkovitch, José Filho   +4 more
doaj   +3 more sources

IMAGENS DO FEMININO NO BANQUETE DE PLATÃO: SÓCRATES E A FLAUTISTA

Kínesis, 2021
O presente trabalho tem como objetivo central a análise e discussão da questão do feminino nos cinco primeiros discursos que compõem um dos mais célebres diálogos platônicos, O Banquete.
Vicente Thiago Freire Brazil
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Pausânias no Banquete de Platão: Encômio ao Eros sofístico [Pausanias in Plato’s Symposium: encomium to Eros sophistic]

Kalagatos, 2017
O presente artigo tem como objetivo refletir sobre os fundamentos teóricos que balizam os argumentos apresentados por Pausânias em seu célebre discurso no Banquete.
Vicente Brazil
doaj  

Issues and Challenges in Open and Distance e-Learning: Perspectives from the Philippines

International Review of Research in Open and Distributed Learning, 2016
Rapid advances in information and communications technology in the digital age have brought about significant changes in the practice of distance education (DE) worldwide.
Patricia Brazil Arinto
doaj   +1 more source